Pestivirus Species Potential Adventitious Contaminants of Biological Products

Abstract

Bovine Viral Diarrhea virus species of the genus Pestivirus, important pathogens affecting zootechnics worldwide, have been reported as adventitious contaminants of biological products for veterinary and human use. The Bovine Viral Diarrhea virus 1 species showed potential for an emerging zoonosis. According to World Organization for Animal Health (Office International des Epizooties: OIE), Bovine Viral Diarrhea is a notifiable disease of importance to international trade. Recently, Bovine Viral Diarrhea virus 3 tentative species have been isolated from Brazil and Thailand. The virus has been diffused from South America to other countries probably through the commercialization of contaminated fetal bovine serum.