Synthesis and Structural Characterization of Two Types of Chromene Derivatives Containing Pyrazolone or Indol-2-one: Reaction and Chemoselectivity of Carbonyl and Aldehyde Groups

Abstract

: Under the catalytic conditions of tetrahydropyrrole, an addition-elimination reaction of chromone aldehyde with methylpyrazolone or 2-indolinone is carried out to obtain two kinds of chromene derivatives containing pyrazolone or indol-2-one. The structures are identified by 1 H NMR, 13 C NMR, HPLC, HRMS and melting point measurements.