A 3-month mastication intervention improves recognition memory

Q3 Medicine

Nutrition and Healthy Aging Pub Date : 2019-01-01 DOI:10.3233/NHA-180047

Curie Kim, S. Miquel, S. Thuret

{"title":"A 3-month mastication intervention improves recognition memory","authors":"Curie Kim, S. Miquel, S. Thuret","doi":"10.3233/NHA-180047","DOIUrl":null,"url":null,"abstract":"BACKGROUND: Decreased mastication due to edentulism in both humans and animals have a negative impact on brain function and cognition. Human populations have shown a close association between masticatory function, cognitive status and age-related neurodegeneration in the elderly. Evidence shows that mastication during tasks may have an acute positive impact on normal cognitive function, such as sustained attention. However, there is a lack of evidence showing the long-term effects of changes in habitual masticatory behaviour on cognition. OBJECTIVE: To investigate the impact of a 3-month mastication intervention on cognitive function in healthy older adults. METHODS: 53 participants aged 45–70 years old were required to chew mint-flavoured sugar free chewing gum for 10 minutes, 3 times a day over 3 months. Pattern separation and recognition memory was measured using the Mnemonic Similarity Task. Questionnaires were administered to measure changes in mood, anxiety, and sleep quality. RESULTS: Extended periods of mastication gave rise to a significant improvement in recognition memory compared to a non-chewing control group. CONCLUSION: With an ageing population, non-medical interventions are imperative to delay age-related cognitive decline. Further work needs to be carried out in larger populations to validate the findings in this study and elucidate potential mechanisms.","PeriodicalId":37419,"journal":{"name":"Nutrition and Healthy Aging","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/NHA-180047","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition and Healthy Aging","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3233/NHA-180047","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 3

Abstract

BACKGROUND: Decreased mastication due to edentulism in both humans and animals have a negative impact on brain function and cognition. Human populations have shown a close association between masticatory function, cognitive status and age-related neurodegeneration in the elderly. Evidence shows that mastication during tasks may have an acute positive impact on normal cognitive function, such as sustained attention. However, there is a lack of evidence showing the long-term effects of changes in habitual masticatory behaviour on cognition. OBJECTIVE: To investigate the impact of a 3-month mastication intervention on cognitive function in healthy older adults. METHODS: 53 participants aged 45–70 years old were required to chew mint-flavoured sugar free chewing gum for 10 minutes, 3 times a day over 3 months. Pattern separation and recognition memory was measured using the Mnemonic Similarity Task. Questionnaires were administered to measure changes in mood, anxiety, and sleep quality. RESULTS: Extended periods of mastication gave rise to a significant improvement in recognition memory compared to a non-chewing control group. CONCLUSION: With an ageing population, non-medical interventions are imperative to delay age-related cognitive decline. Further work needs to be carried out in larger populations to validate the findings in this study and elucidate potential mechanisms.

查看原文本刊更多论文

3个月的咀嚼干预可以改善识别记忆

背景:在人类和动物中，由于牙齿缺失导致的咀嚼减少对大脑功能和认知有负面影响。在老年人中，咀嚼功能、认知状态和与年龄相关的神经变性之间存在着密切的联系。有证据表明，在任务中咀嚼可能会对正常的认知功能产生积极的影响，比如持续的注意力。然而，缺乏证据表明习惯咀嚼行为的改变对认知的长期影响。目的:探讨3个月咀嚼干预对健康老年人认知功能的影响。方法:53名年龄在45-70岁之间的参与者被要求咀嚼薄荷味无糖口香糖10分钟，每天3次，持续3个月。模式分离和识别记忆采用助记相似任务进行测试。通过问卷调查来衡量情绪、焦虑和睡眠质量的变化。结果:与不咀嚼的对照组相比，延长咀嚼时间可以显著改善识别记忆。结论:随着人口老龄化，非医疗干预措施是必要的，以延缓年龄相关的认知能力下降。进一步的工作需要在更大的人群中进行，以验证本研究的发现并阐明潜在的机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nutrition and Healthy Aging Agricultural and Biological Sciences-Food Science

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： Nutrition and Healthy Aging is an international forum for research on nutrition as a means of promoting healthy aging. It is particularly concerned with the impact of nutritional interventions on the metabolic and molecular mechanisms which modulate aging and age-associated diseases, including both biological responses on the part of the organism itself and its micro biome. Results emanating from both model organisms and clinical trials will be considered. With regards to the latter, the journal will be rigorous in only accepting for publication well controlled, randomized human intervention trials that conform broadly with the current EFSA and US FDA guidelines for nutritional clinical studies. The journal will publish research articles, short communications, critical reviews and conference summaries, whilst open peer commentaries will be welcomed.