Metastatic Renal Cell Carcinoma to the Nasal Cavity, but after 17 Years

Allon I, Silenikov I, Schaffer M, Forer B, Livoff A
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Abstract

We present a case of a 64-year-old man with a bilateral nasal obstruction. An endoscopic biopsy taken from the mass revealed a vascular clear cell tumor underneath an intact Schneiderian membrane compatible with a renal cell carcinoma. Following inquiry, it was revealed that the patient had gone through right radical nephrectomy for renal cell carcinomas 17 years prior to admission, a fact that was not known when the biopsy was taken. A following workup showed areas suspicious for metastases in lungs and maxillary sinuses. The patient started treatment with Sunitinib. On five months follow- up, the lung lesions had regressed.
转移到鼻腔的肾细胞癌,但已经17年了
我们报告一例64岁男性双侧鼻塞。从肿物上取下的内镜活检显示在完整的施耐德膜下有一个血管透明细胞瘤,与肾细胞癌一致。经询问,发现患者在入院前17年因肾细胞癌行过右侧根治性肾切除术,活检时不知道这一事实。后续检查显示肺部和上颌窦可疑转移灶。患者开始使用舒尼替尼治疗。随访5个月后,肺部病变消退。
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