Treatment of Dementia Symptoms: Scoping Review of Complementary and Alternative Medicine Approaches

M. deBoer, Yau Ehy, A. Andriianova, Bérénos Im, Van Dommelen Jem, A. Visser
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Abstract

Aim: This article presents an overview of complementary and alternative medicine approaches (CAM) to treat symptoms of dementia. Method: Retrieving of studies from several bibliographic databases (January 1998 to March 2020) applying prespecified selection criteria and methodological quality assessment. Results: CAM approaches reduce symptoms of dementia, slow down the progression, and create relief for patients, while not intending to prevent and cure dementia. Psychological interventions are helpful for families to establish more and better interactions with patients. Traditional Chinese medicine (acupuncture and Chinese herbal medicine) is promising strategies to treat memory loss. Homeopathy might be effective in treating symptoms of dementia. Light therapy reduces sleep deprivation, depression and agitation. Aroma & music therapy improve quality of life and recalling thoughts and feelings. Nutrition shows variant effects on dementia symptoms and development of AD, such as with folate-rich foods, low-fat dairy products, and intake of fish or omega-3 fats. Red grapes show a protective effect on AD and VaD. Exercises enhance memory. Controlled Multisensory Therapy (Snoezel therapy) shows short-term effects on mood and behaviour. Conclusion: CAM is an alternative for conventional treatments, like medicines to relieve symptoms, however good CAM trials are lacking. Analysed studies were of low quality, having no control groups, small samples, and only case and animal studies. Research on a combination of conventional and CAM is needed to show the additional effects on conventional treatments.
痴呆症状的治疗:补充和替代医学方法的范围审查
目的:本文介绍了补充和替代医学方法(CAM)治疗痴呆症状的概述。方法:采用预定的选择标准和方法学质量评价方法,检索1998年1月至2020年3月期间多个文献数据库中的研究。结果:CAM方法减轻了痴呆症的症状,减缓了进展,并为患者创造了缓解,而不是为了预防和治愈痴呆症。心理干预有助于家庭与患者建立更多更好的互动。传统中医(针灸和中草药)是治疗记忆丧失的有希望的策略。顺势疗法可能对治疗痴呆症状有效。光疗法可以减少睡眠剥夺、抑郁和躁动。香气和音乐疗法提高生活质量和回忆的思想和感情。营养对痴呆症状和阿尔茨海默病的发展有不同的影响,比如富含叶酸的食物、低脂乳制品、摄入鱼或omega-3脂肪。红葡萄对AD和VaD有保护作用。锻炼可以增强记忆力。控制多感觉疗法(Snoezel疗法)显示出对情绪和行为的短期影响。结论:CAM是常规治疗的替代方案,如药物缓解症状,但缺乏良好的CAM试验。分析的研究质量低,没有对照组,样本小,只有病例和动物研究。需要对常规疗法和辅助治疗相结合进行研究,以显示常规疗法的额外效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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