How to obtain evidence of vertical transmission of coronavirus according to serological test of specific IgM and IgG antibodies

Q4 Medicine

中华围产医学杂志 Pub Date : 2020-04-15 DOI:10.3760/CMA.J.CN113903-20200402-00301

Chen Wang, Yihua Zhou, Huixia Yang

引用次数: 1

Abstract

Whether 2019 novel coronavirus can be vertically transmitted to fetuses is a major concern, while how to obtain evidence of vertical transmission in viral infected pregnant women is the key. Virological and serological evidence is valuable to clarify this issue. However, longitudinal follow-up of infants for at least 3-6 months after birth and dynamic changes of specific antibodies of the mothers is essential when serological results are used to confirm or exclude vertical transmission. Key words: Coronavirus infections; Infectious disease transmission, vertical; Immunoglobulin M; Immunoglobulin G

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如何根据特异性IgM和IgG抗体的血清学检测获得冠状病毒垂直传播的证据

新型冠状病毒是否会垂直传播给胎儿是人们关注的焦点，而如何获得病毒感染孕妇垂直传播的证据是关键。病毒学和血清学证据有助于澄清这一问题。然而，当使用血清学结果确认或排除垂直传播时，必须对出生后至少3-6个月的婴儿进行纵向随访，并对母亲的特异性抗体进行动态变化。关键词:冠状病毒感染;传染病传播，垂直传播;免疫球蛋白M;免疫球蛋白G

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中华围产医学杂志 Medicine-Obstetrics and Gynecology

CiteScore

0.70

自引率

0.00%

发文量

4446

期刊介绍： Chinese Journal of Perinatal Medicine was founded in May 1998. It is one of the journals of the Chinese Medical Association, which is supervised by the China Association for Science and Technology, sponsored by the Chinese Medical Association, and hosted by Peking University First Hospital. Perinatal medicine is a new discipline jointly studied by obstetrics and neonatology. The purpose of this journal is to "prenatal and postnatal care, improve the quality of the newborn population, and ensure the safety and health of mothers and infants". It reflects the new theories, new technologies, and new progress in perinatal medicine in related disciplines such as basic, clinical and preventive medicine, genetics, and sociology. It aims to provide a window and platform for academic exchanges, information transmission, and understanding of the development trends of domestic and foreign perinatal medicine for the majority of perinatal medicine workers in my country.