Clinical analysis of acute pulmonary embolism with type 2 diabetes mellitus

Feng Chen, Xuefeng Han, Qingrong Nie, Lei Zhang
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Abstract

Objective To explore the clinical features and recurrence rates of acute pulmonary embolism (APE) with type 2 diabetes mellitus(DM2). Methods 126 patients with acute pulmonary embolism were retrospectively analysed from January 2010 to December 2015. All patients were divided into two groups:observation group (APE with DM2,43 cases) and control group(APE without DM2,83 cases).The differences of clinical manifestations, complications,laboratory results,thrombus localizations,risk stratification and the recurrence rates of acute pulmonary embolism were analysed between the two groups. Results There were no significant differences in age,sex and clinical manifestations between the two groups. The combination of respiratory failure,coronary heart disease and pneumonia were more frequently seen in observation group(P<0.05). The level of creatine kinase, lactate dehydrogenase, fasting blood glucose,cTnI,NT-pro-BNP, CREA were obviously higher than control group(P<0.05). A higher risk stratification and recurrence rate were observed in the bservation group(P<0.05). Conclusion Patients with acute pulmonary embolism and type 2 diabetes mellitus are more serious and more affected by complications and a higher recurrence rate,thus,we should give more attention to these patients and reduce the recurrence rate. Key words: Pulmonary embolism; Type 2 diabetes mellitus; Recurrence rate
急性肺栓塞合并2型糖尿病临床分析
目的探讨急性肺栓塞(APE)合并2型糖尿病(DM2)的临床特点及复发率。方法对2010年1月~ 2015年12月收治的126例急性肺栓塞患者进行回顾性分析。所有患者分为两组:观察组(APE + DM2,43例)和对照组(APE + DM2,83例)。分析两组急性肺栓塞的临床表现、并发症、实验室检查结果、血栓定位、危险分层及复发率的差异。结果两组患者在年龄、性别、临床表现上无明显差异。观察组合并呼吸衰竭、冠心病、肺炎发生率较高(P<0.05)。各组肌酸激酶、乳酸脱氢酶、空腹血糖、cTnI、NT-pro-BNP、CREA水平均显著高于对照组(P<0.05)。观察组的危险分层和复发率均高于对照组(P<0.05)。结论急性肺栓塞合并2型糖尿病患者病情严重,并发症多,复发率高,应给予重视,降低复发率。关键词:肺栓塞;2型糖尿病;复发率
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