Virological Profile of Acute Respiratory Infections in Children at Dakar CHU

I. Ba, G. Diagne, A. Diallo, N. Dia, E. Fall, A. Mbaye, A. Kane, A. M. Coundoul, S. Sow, K. Bop, Ousseynou Ndiaye
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Abstract

Introduction: Acute respiratory infections (ARIs) are a global public health priority. They are the leading cause of morbidity and mortality in children, especially in developing countries. The main objective of this study was to see mainly the virological aspects in ARI in children in Senegalese hospitals Methodology: We had conducted a prospective descriptive mono-centric study over a period of one year (from July 01, 2017 to June 30, 2018) at the Albert Royer National Children's Hospital in Dakar. Results: The hospital frequency for acute respiratory infections in children was 3.7%. The average age was 23.7 months with extremes between 1 month and 144 months. The peaks of consultations were found in August, March and April with respectively 22%, 15.6% and 12.8%. Fever, respiratory distress and pulmonary condensation syndrome were the main signs found on examination in our patients. Virologic tests were positive in 80.7%. The viruses most frequently found in the samples were the Rhinovirus in 33% of the samples, the respiratory syncytial virus in 24.8% and the coronavirus in 15.6%. Among the diagnoses retained, pneumonia was predominant and found in 61 of the cases, or a prevalence of 59.9%, followed by acute bronchiolitis with a prevalence of 16.51%. The average length of hospital stay was 10 days. Conclusion: Acute respiratory infections in children are still a public health problem in developing countries; children under the age of five years are the most affected, hence the need to strengthen programs to fight ARI. The identification of germs is essential in the treatment and epidemiological surveillance in our regions.
达喀尔地区儿童急性呼吸道感染病毒学分析
急性呼吸道感染(ARIs)是一个全球公共卫生重点问题。它们是儿童发病和死亡的主要原因,特别是在发展中国家。本研究的主要目的是了解塞内加尔医院儿童急性呼吸道感染的病毒学方面。方法:我们在达喀尔阿尔伯特罗耶国家儿童医院进行了一项为期一年(2017年7月1日至2018年6月30日)的前瞻性描述性单中心研究。结果:儿童急性呼吸道感染住院率为3.7%。平均年龄23.7个月,极值为1 ~ 144个月。咨询高峰出现在8月、3月和4月,分别占22%、15.6%和12.8%。发热、呼吸窘迫、肺冷凝综合征是本组患者的主要检查征象。病毒学检测阳性的占80.7%。样本中最常见的病毒是鼻病毒(33%)、呼吸道合胞病毒(24.8%)和冠状病毒(15.6%)。在保留的诊断中,以肺炎为主,61例为肺炎,患病率为59.9%,其次是急性细支气管炎,患病率为16.51%。平均住院时间为10天。结论:儿童急性呼吸道感染仍然是发展中国家的一个公共卫生问题;五岁以下儿童受影响最大,因此需要加强防治急性呼吸道感染的规划。在我们地区的治疗和流行病学监测中,细菌的鉴定是必不可少的。
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