Dynamics and scale-up of thePharmaceutical molecule

S. Gavanji
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Abstract

The use of biopharmaceuticals dates from the 19th century and within 5–10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced significant growth in the production and approval of recombinant proteins such as interferon’s (IFN α, β, and γ) and growth hormones. The production of biopharmaceuticals, known as bioprocess, involves a wide range of techniques.
药物分子的动力学和放大
生物制药的使用可追溯到19世纪,在5-10年内,所有正在开发的药物中高达50%将是生物制药。在20世纪80年代,生物制药行业在生产和批准重组蛋白如干扰素(IFN α, β和γ)和生长激素方面经历了显著的增长。生物制药的生产,被称为生物工艺,涉及广泛的技术。
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