Complete Response of Metastatic Pancreatic Cancer In A CHEK2 Mutation Carrier Treated With Platinum-Based Therapy- A Case Report And Literature Review

Abstract

A 53-year-old woman presented with abdominal pain and obstructive jaundice and was diagnosed with metastatic pancreatic adenocarcinoma. She received FOLFIRINOX chemotherapy and achieved complete response. Germline testing detected CHEK2 and treatment was switched to Olaparib maintenance.