Vismodegib for Patients with Advanced Basal Cell Carcinoma: One Center’s Experience

Abstract

atinocytes located in the basal epidermis, which firstly infiltrate the epidermis and then the dermis. Clinically, it usually occurs on the face and neck.1,2 BCC has five main clinical variants: nodular-ulcerative, superficial, sclerosing-morphea, pigment-ulcerated and fibroepithelial.3 The incidence rate of BCCs in the US reportedly spiked by 145% between 2000 and 2010 with the reasons for this significant increase including the aging of the patient population, increased awareness of the overall population, increased number of surgical cases, better record-keeping, and UV radiation.4