The Alteration of Clinical and Laboratory Signs and Symptoms of COVID-19 in Re-infection: A Case Report

Leyli Yekefallah, P. Namdar, S. Mohammadi
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引用次数: 0

Abstract

Background: Patients can be carriers of the virus for a long time or become re-infected or re-infected following the use of immunosuppressive drugs. Clinical manifestations in patients are very diverse and can range from asymptomatic to severe illness with death. Patients may also present with manifestations such as coagulation disorders, cardiac dysfunction and arrhythmias, acute coronary syndrome, kidney injury, liver injury, Refer to diabetic hyperglycemia and ketoacidosis. This is an essential point in the prevention of Coronavirus Disease 19 (COVID-19). Case Presentation: We reported a case in which the Polymerase Chain Reaction (PCR) test was positive after re-negative after 5 months. Moreover, the patient presented different and more severe symptoms than the previous infection, as the genetic difference between the strains increased over time. Conclusion: As a result, immunization may become more complicated, and different clinical pictures occur; thus, this condition can challenge vaccine immunization.
再感染后COVID-19临床和实验室体征和症状的改变:1例报告
背景:患者可能长期是病毒携带者,或在使用免疫抑制药物后再次感染或再感染。患者的临床表现非常多样,可以从无症状到严重疾病并死亡。患者还可出现凝血功能障碍、心功能不全、心律失常、急性冠状动脉综合征、肾损伤、肝损伤等表现,参考糖尿病高血糖和酮症酸中毒。这是预防2019冠状病毒病(COVID-19)的关键。病例介绍:我们报告了一例聚合酶链反应(PCR)试验在5个月后再次阴性后阳性的病例。此外,由于菌株之间的遗传差异随着时间的推移而增加,患者表现出与先前感染不同且更严重的症状。结论:免疫接种可能会变得更加复杂,出现不同的临床表现;因此,这种情况可能对疫苗免疫构成挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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