Incidence and Predictors of Diabetic Ketoacidosis among Children with Diabetes

Birtukan Assefa, Haymanot Zeleke
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Abstract

Diabetic ketoacidosis remains a relevant problem in children with diabetes. Its incidence is wide ranging across the world due to quality of health care services and socioeconomic circumstances; in resent study in Ethiopia high incidence was observed. The interacting factors for diabetic ketoacidosis development are absolute or relative insulin deficiency. In established diabetes diabetic ketoacidosis develops when treatment fails to adequately control blood glucose concentration. Treatment failure can be due to medication non adherence and relative ineffectiveness of insulin when insulin action is antagonized by physiological stress such as infection and inappropriate storage of insulin at home. Diabetic ketoacidosis and its associated complications can be prevented with proper diabetic education and treatment.
糖尿病儿童糖尿病酮症酸中毒的发病率及预测因素
糖尿病酮症酸中毒仍然是儿童糖尿病患者的一个相关问题。由于卫生保健服务的质量和社会经济环境,其发病率在世界各地范围很广;在最近的研究中,埃塞俄比亚的发病率很高。糖尿病酮症酸中毒发生的相互作用因素是绝对或相对胰岛素缺乏。在已确诊的糖尿病患者中,当治疗未能充分控制血糖浓度时,会发生糖尿病酮症酸中毒。治疗失败可能是由于药物的不依从性和胰岛素的相对无效,当胰岛素的作用被生理应激(如感染和家中不适当的胰岛素储存)拮抗时。糖尿病酮症酸中毒及其相关并发症可通过适当的糖尿病教育和治疗加以预防。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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