{"title":"Crohn’s Disease: A Curable Disease Held Hostage?","authors":"G. Monif","doi":"10.33552/ajgh.2021.02.000549","DOIUrl":null,"url":null,"abstract":"(MAP) could be so challenged to abort mycobacterium replication that its inherent immune system became fixed within immunological memory. Owing to the loss of immunological tolerance, every time the baby’s immune system encountered MAP. it would again respond by elaborating pro-inflammatory cytokines directed at MAP at its points of mucosal attachment to the gastrointestinal mucosa and its antigen processing. A major factor complicating attempts to construct meaningful comparative therapeutic groups for clinical trials is the degree to which the gastrointestinal microbiota has","PeriodicalId":72038,"journal":{"name":"Academic journal of gastroenterology & hepatology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Academic journal of gastroenterology & hepatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33552/ajgh.2021.02.000549","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
(MAP) could be so challenged to abort mycobacterium replication that its inherent immune system became fixed within immunological memory. Owing to the loss of immunological tolerance, every time the baby’s immune system encountered MAP. it would again respond by elaborating pro-inflammatory cytokines directed at MAP at its points of mucosal attachment to the gastrointestinal mucosa and its antigen processing. A major factor complicating attempts to construct meaningful comparative therapeutic groups for clinical trials is the degree to which the gastrointestinal microbiota has