Determination of Meropenem, Ceftazidime and Piperacillin Levels in Serum and Meropenem in Cerebrospinal Fluid by Liquid Chromatography for Routine Quantification

Stefan Günther, A. Reimer, H. Vogl, Stephan Spenke, Hanns-Christian Dinges, A. Schubert, Leopold Hj Eberhart, G. Geldner
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引用次数: 1

Abstract

((4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-Abstract Objective: Therapeutic drug monitoring (TDM) of β-lactam antibiotics is a commonly used to prevent treatment failures in critically ill patients. A quick and simple high-performance liquid chromatography (HPLC) assay for the determination of meropenem, ceftazidime and piperacillin in human serum and meopenem in
液相色谱法测定血清中美罗培南、头孢他啶、哌拉西林及脑脊液中美罗培南的常规定量
[(4R,5S,6S)-3-[[(3S,5S)-5-[(二甲氨基)羰基]-3]摘要目的:β-内酰胺类抗生素的治疗性药物监测(TDM)是预防危重患者治疗失败的常用手段。建立了快速简便的高效液相色谱法测定人血清中美罗培南、头孢他啶和哌拉西林的含量
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