Abdominal Aortic Aneurysmatic Sac Shrinking is the New Paradigm after Endovascular Treatment

G. Espinosa, P. Saad, Giovanni di Luccio, Pedro Duarte Vaz, L. Baptista, C. Magliano
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Abstract

Objectives: Aneurysmal Sac (SAC) absorption after endovascular treatment (EVAR) of Abdominal Aortic Aneurysms (AAA) is related to a better prognosis but its long-term mandatory and predictive factors remain unclear. Our study aims to assess the impact of its total resorption on patient survival, as well as the factors that favor resorption. Methods: We followed a187 patients who underwent EVAR with a fully thrombosed SAC for 22 years in the postoperative control of Angio-CT. We established the significance of the factors for SAC resorption by logistic regression models, evaluating comorbidities, diameter, sex and age of the patient. We also compared the impact of absorption sac absorption with survival. Results: Diameter and age were significant for the resorption of the SAC together or even independently (p-value <0.001), the diameter (OR-0.29) showed a greater influence than age (OR= -0.063). The comorbidities studied and the sex of the patients was not statistically significant. Patients who had significant absorption (≥ 10 mm) had a survival rate of 12.72 ± 0.96 years, those with moderate absorption (5 mm to 9 mm) had of 8.34 ± 1.62 years and those without significant resorption or growth had 3.27 ± 0.48 years (p-value <0.001). Among patients with absorption of ≥ 5 mm in the first year, we found greater chances of total absorption (OR=4.72 p-value <0.001). Conclusion: Total sac resorption proved to be an important prognostic factor for patient survival after EVAR. The age of the patient and mainly the initial diameter of the sac were the factors significantly associated with the resorption of the sac.
腹主动脉瘤囊萎缩是血管内治疗的新范式
目的:腹主动脉瘤(AAA)血管内治疗(EVAR)后动脉瘤囊(Sac)的吸收与较好的预后有关,但其长期强制性和预测因素尚不清楚。我们的研究旨在评估其总吸收对患者生存的影响,以及有利于吸收的因素。方法:我们对187例伴有完全血栓形成SAC的EVAR患者进行了22年的术后血管ct控制。我们通过logistic回归模型,评估患者的合并症、直径、性别和年龄,确定影响SAC吸收的因素的重要性。我们还比较了吸收囊吸收对生存率的影响。结果:直径和年龄共同或单独影响SAC的吸收(p值<0.001),直径(or = 0.29)的影响大于年龄(or = -0.063)。研究的合并症和患者的性别无统计学意义。明显吸收(≥10 mm)患者生存率为12.72±0.96年,中度吸收(5 mm ~ 9 mm)患者生存率为8.34±1.62年,无明显吸收或生长的患者生存率为3.27±0.48年(p值<0.001)。在第一年吸收≥5mm的患者中,我们发现总吸收的机会更大(OR=4.72 p值<0.001)。结论:囊腔完全吸收是影响EVAR患者生存的重要因素。患者的年龄,主要是囊的初始直径是与囊吸收显著相关的因素。
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