Utilization of KNApSAcK Family Databases for Developing Herbal Medicine Systems

S. Wijaya, Yuki Tanaka, M. Altaf-Ul-Amin, Aki Morita, F. Afendi, I. Batubara, N. Ono, L. K. Darusman, S. Kanaya
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引用次数: 9

Abstract

Recently, the use of traditional medicines for medical treatment and maintaining good health is increasing. This condition has been followed by the increasing number of research activities, publications and databases of crude drug systems to support the scientific aspects of traditional medicines. Nevertheless, the information about traditional medicines is scattered in an unorganized manner and the existing traditional medicine databases have been stored by different database schemas. Therefore, a standardized tool that integrates and provides information about various herbal medicines is needed. In this study, we developed a mobile application with Waterfall Method, called as Herbal Medicine Systems, for various kinds of crude drug systems as a reference of traditional medicines. The KNApSAcK Family Databases were used as a role model to design the database schemas of crude drug systems by using data warehouse pre-processing technique. The Herbal Medicine Systems application is preloaded with 336 and 5,310 Kampo and Jamu formulas respectively from the KNApSAcK Kampo and KNApSAcK Jamu databases. In addition, the Herbal Medicine Systems can predict the efficacy of crude drug combinations by using Random Forest classifier developed based on the formulation of Indonesian Jamu with the average accuracy of 90%.
利用背包家族数据库开发中草药系统
最近,越来越多的人使用传统药物进行医疗和保持身体健康。在这种情况下,有越来越多的研究活动、出版物和粗药物系统数据库支持传统药物的科学方面。然而,传统医药信息分散、无组织,现有的传统医药数据库采用不同的数据库模式存储。因此,需要一种整合并提供各种草药信息的标准化工具。在本研究中,我们使用瀑布法开发了一个移动应用程序,名为草药系统,用于各种生药系统,作为传统药物的参考。以KNApSAcK家族数据库为例,采用数据仓库预处理技术设计了生药系统数据库模式。草药系统应用程序分别预装了来自KNApSAcK Kampo和KNApSAcK Jamu数据库的336和5,310种Kampo和Jamu配方。此外,草药系统还可以利用基于印尼加木配方开发的随机森林分类器预测生药组合的疗效,平均准确率为90%。
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Journal of Computer Aided Chemistry
Journal of Computer Aided Chemistry CHEMISTRY, MULTIDISCIPLINARY-
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