Optimal control in a mathematical model of a spread of the obesity epidemic and its impact on diabetes

IF 0.5 Q4 COMPUTER SCIENCE, INFORMATION SYSTEMS
Abdelbar EL Mansouri, I. Smouni, B. Khajji, A. Labzai, M. Belam, Y. Tidli
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引用次数: 2

Abstract

. The obesity epidemic is associated with several cardiovascular risk factors, including diabetes mellitus, dyslipidemia, and hypertension. Insulin resistance is believed to play a crucial role in the emergence of various health problems. Apart from genetic factors, obesity, particularly abdominal obesity, is a major contributor to the onset of diabetes. In this study, we present a mathematical model that captures the interplay between the prevalence of obesity and diabetes, and we investigate the adverse effects of excess weight on the well-being of diabetic individuals. Our approach employs Pontryagin’s maximum principle to determine the optimal control strategies, and we solve the resulting system through iterative methods. Finally, we perform numerical simulations using Matlab to validate our theoretical analysis.
肥胖症流行及其对糖尿病影响的数学模型的最优控制
. 肥胖流行与几种心血管危险因素有关,包括糖尿病、血脂异常和高血压。胰岛素抵抗被认为在各种健康问题的出现中起着至关重要的作用。除了遗传因素外,肥胖,特别是腹部肥胖,是糖尿病发病的主要因素。在这项研究中,我们提出了一个数学模型,该模型捕捉了肥胖患病率和糖尿病之间的相互作用,我们调查了超重对糖尿病患者健康的不利影响。我们的方法采用庞特里亚金极大值原理来确定最优控制策略,并通过迭代方法求解得到的系统。最后,利用Matlab进行了数值模拟,验证了理论分析的正确性。
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来源期刊
Communications in Mathematical Biology and Neuroscience
Communications in Mathematical Biology and Neuroscience COMPUTER SCIENCE, INFORMATION SYSTEMS-
CiteScore
2.10
自引率
15.40%
发文量
80
期刊介绍: Communications in Mathematical Biology and Neuroscience (CMBN) is a peer-reviewed open access international journal, which is aimed to provide a publication forum for important research in all aspects of mathematical biology and neuroscience. This journal will accept high quality articles containing original research results and survey articles of exceptional merit.
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