Optimal prevention of HIV-AIDS with emphasis on unprotected and unnatural canal activities: a deterministic modelling perspective

IF 0.5 Q4 COMPUTER SCIENCE, INFORMATION SYSTEMS
D. Otoo, Hawa Edusei, Albert Gyan, Daniel Gyamfi, Shaibu Osman
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引用次数: 0

Abstract

. HIV accounts for more than thirty three million death and approximately thirty eight million infected cases since it’s inception. The disease unfolds in three stages; Chronic, Acute and fully blown AIDS. Adhering to preventive protocols such as use of condoms, preventing oneself from unprotected sex and limiting one’s sexual partners could help minimize the disease spread. In this study, a deterministic model for HIV-AIDS is formulated. The equilibrium points, local and global stability of the equilibrium points, and HIV reproductive rate were determined and interpreted. The model was extended to optimal control by simulating the optimality system. This was done by incorporating the use of condoms and education of susceptible population as intervention strategies. It was established that the best and most effective control strategy was optimal education and sensitisation of susceptible population.
艾滋病毒/艾滋病的最佳预防,重点是无保护和非自然的运河活动:确定性模型的观点
。自艾滋病毒出现以来,已有超过3300万人死亡,约有3800万感染病例。这种疾病分为三个阶段;慢性、急性和全面爆发的艾滋病。遵守预防措施,如使用避孕套、避免无保护的性行为和限制性伴侣,可以帮助最大限度地减少疾病的传播。本研究建立了HIV-AIDS的确定性模型。确定并解释了平衡点、平衡点的局部稳定性和全局稳定性以及HIV繁殖率。通过对最优系统的仿真,将模型扩展到最优控制。这是通过将使用避孕套和对易感人群进行教育作为干预策略来实现的。结果表明,最有效的控制策略是对易感人群进行最佳教育和敏感化。
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来源期刊
Communications in Mathematical Biology and Neuroscience
Communications in Mathematical Biology and Neuroscience COMPUTER SCIENCE, INFORMATION SYSTEMS-
CiteScore
2.10
自引率
15.40%
发文量
80
期刊介绍: Communications in Mathematical Biology and Neuroscience (CMBN) is a peer-reviewed open access international journal, which is aimed to provide a publication forum for important research in all aspects of mathematical biology and neuroscience. This journal will accept high quality articles containing original research results and survey articles of exceptional merit.
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