Monkeypox mathematical model with surveillance as control

IF 0.5 Q4 COMPUTER SCIENCE, INFORMATION SYSTEMS
Uchenna Michael, L. Omenyi, Elebute Kafayat, E. Nwaeze, Offia Akachukwu, G. Ozoigbo, Monday Ekhator
{"title":"Monkeypox mathematical model with surveillance as control","authors":"Uchenna Michael, L. Omenyi, Elebute Kafayat, E. Nwaeze, Offia Akachukwu, G. Ozoigbo, Monday Ekhator","doi":"10.28919/cmbn/7781","DOIUrl":null,"url":null,"abstract":". A compartmental mathematical model of the transmission dynamics of the monkeypox virus (MPXV) was developed and analyzed. The model incorporates proper surveillance and contact tracing as effective controls. The equilibrium states of the model were obtained and analyzed both locally and globally. The effective reproduction number, R m was obtained and the sensitivity of the model parameters were studied using R m as the threshold of transmission. When the infection becomes endemic, R m (cid:117) 1 , the model exhibits a backward bifurcation but R m < 1 which means that the interventions tend to MPXV containment. Numerical simulations to bespeak our findings and discussions are provided. Our result shows that surveillance and contact tracing are effective for the containment of MPXV in the absence of a perfect vaccine.","PeriodicalId":44079,"journal":{"name":"Communications in Mathematical Biology and Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Communications in Mathematical Biology and Neuroscience","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.28919/cmbn/7781","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"COMPUTER SCIENCE, INFORMATION SYSTEMS","Score":null,"Total":0}
引用次数: 2

Abstract

. A compartmental mathematical model of the transmission dynamics of the monkeypox virus (MPXV) was developed and analyzed. The model incorporates proper surveillance and contact tracing as effective controls. The equilibrium states of the model were obtained and analyzed both locally and globally. The effective reproduction number, R m was obtained and the sensitivity of the model parameters were studied using R m as the threshold of transmission. When the infection becomes endemic, R m (cid:117) 1 , the model exhibits a backward bifurcation but R m < 1 which means that the interventions tend to MPXV containment. Numerical simulations to bespeak our findings and discussions are provided. Our result shows that surveillance and contact tracing are effective for the containment of MPXV in the absence of a perfect vaccine.
以监测为控制的猴痘数学模型
。建立并分析了猴痘病毒(MPXV)传播动力学的区室数学模型。该模型将适当的监测和接触者追踪作为有效的控制措施。得到了模型的局部和全局平衡状态,并对其进行了分析。得到了有效繁殖数R m,并以R m作为传播阈值,研究了模型参数的敏感性。当感染成为地方病时,R m (cid:117) 1,模型呈现向后分叉,但R m < 1,这意味着干预措施倾向于抑制MPXV。数值模拟说明了我们的发现和讨论。我们的研究结果表明,在没有完美疫苗的情况下,监测和接触者追踪对遏制MPXV是有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Communications in Mathematical Biology and Neuroscience
Communications in Mathematical Biology and Neuroscience COMPUTER SCIENCE, INFORMATION SYSTEMS-
CiteScore
2.10
自引率
15.40%
发文量
80
期刊介绍: Communications in Mathematical Biology and Neuroscience (CMBN) is a peer-reviewed open access international journal, which is aimed to provide a publication forum for important research in all aspects of mathematical biology and neuroscience. This journal will accept high quality articles containing original research results and survey articles of exceptional merit.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信