IgA Crescentic Nephropathy Post COVID-19 Infection: A Case Report

Abstract

Background: Since the Coronavirus Disease 2019 (COVID-19) outbreak, individuals affected by COVID19 may be at risk of acquiring certain forms of glomerular disease. Several biopsy researches reveal that acute tubular injury, as well as glomerular nephropathy were common histological findings. However, to our knowledge, there is limited data regarding de novo diagnosis of IgA vasculitis in an adult following a COVID-19 infection. Case presentation: In the present case report, we document a 24-year-old Bahraini woman with new onset hypertension, microhematuria, proteinuria and decreased renal function after she recovered from COVID-19 infection. Renal biopsy after COVID-19 infection was performed and revealed IgA nephropathy without any evidence of COVID-19 infection. After a regimen of immunosuppression and angiotensin converting enzyme inhibitor therapy, the patient recovered and remained stable upon follow-up. Conclusions: When dealing with patient with COVID-19 infection and kidney involvement, it is vital to evaluate the underlying glomerular disease aggravation as well as virus-induced consequences. A kidney biopsy may be necessary to roll out rapidly progressive glomerular disease (RPGN).