Epidemiological and Clinical Features of the First Cohort of Patients Diagnosed with COVID-19 in Bahrain

G. Jassim, M. Naser, F. Almadhoob, Alaa Alakri, Rawaa Al Sayegh, A. Abdul Rahman, Salman Ali
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Abstract

Background: This study investigates the clinical characteristics of the first confirmed cases of Coronavirus disease-2019 (COVID-19) in Bahrain. Methods: This is a retrospective, cross-sectional study including the first 247 confirmed cases in Bahrain. Demographic, clinical, and laboratory data were extracted from electronic medical records. Results: Mean Standard Deviation (SD) age of patients was 44.15 (16.5) years. More males were affected by the disease (61%; 151/274). Mean (SD) of the duration between confirmation and discharge was 9.8 (5.1) days. Of 247 patients, 4 deaths were reported (1.6%); 17.5% (24/137) showed a temperature of >37- on admission, with 4% (6/148) yielding an oxygen saturation of 94% or less. Leukopenia was reported in 36.8% of patients (63/171). One quarter of patients (25.5%) received oseltamivir, 24.7% received hydroxychloroquine sulfate (24.7%), and 1.2% received steroids. Conclusion: In this study, the authors have captured the epidemiological and clinical profiles of the first cases of COVID-19 pertaining to the first wave of the pandemic in Bahrain. The early strict measures may have contributed to the lower incidence as well as lower morbidity and mortality of COVID-19 infection in Bahrain. Major gaps in our knowledge of the clinical spectrum of COVID-19 and its prognosis, outcomes, and associated risk factors indicate the need for further research. Keywords: Bahrain, COVID-19, SARS-CoV-2, Pandemics, Coronavirus
巴林第一批确诊COVID-19患者的流行病学和临床特征
背景:本研究调查巴林首例冠状病毒病-2019 (COVID-19)确诊病例的临床特征。方法:这是一项回顾性的横断面研究,包括巴林的第一批247例确诊病例。从电子病历中提取人口统计、临床和实验室数据。结果:患者平均标准差(SD)年龄为44.15(16.5)岁。受该病影响的男性较多(61%;151/274)。从确诊到出院的平均(SD)时间为9.8(5.1)天。在247例患者中,报告4例死亡(1.6%);17.5%(24/137)患者入院时体温为0.37℃,4%(6/148)患者入院时血氧饱和度为94%或更低。36.8%(63/171)的患者报告白细胞减少。四分之一的患者(25.5%)接受奥司他韦治疗,24.7%接受硫酸羟氯喹治疗(24.7%),1.2%接受类固醇治疗。结论:在本研究中,作者捕获了与巴林第一波大流行有关的第一批COVID-19病例的流行病学和临床概况。早期采取的严格措施可能有助于降低巴林COVID-19感染的发病率和死亡率。我们对COVID-19临床谱及其预后、结局和相关风险因素的认识存在重大差距,这表明需要进一步研究。关键词:巴林,COVID-19, SARS-CoV-2,流行病,冠状病毒
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