Relationship Between Postprandial Blood Glucose, Fasting Insulin, and Glycated Hemoglobin Levels and Early Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus

抗癌研究 Pub Date : 2023-03-30 DOI:10.26689/par.v7i2.4797

Xing-xia Fan, Zhe Li

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Abstract

Objective: To investigate the relationship between postprandial blood glucose (PBG), fasting insulin (FINS), and glycated hemoglobin (HbA1c) levels and early diabetic nephropathy in patients with type 2 diabetes. Methods: 96 cases of type 2 diabetes mellitus treated in our hospital from May 2021 to May 2022 were selected as the research subjects. The patients were divided into two groups according to the urinary albumin excretion rate (UAER), with 53 cases in the type 2 diabetes group (UAER < 30 ?g/min) and 43 cases in the early diabetic nephropathy group (30 ?g/min ? UAER < 300 ?g/min). PBG, FINS, and HbA1c levels were detected in 87 healthy patients. Results: The levels of PBG, FINS, and HbA1c in the early diabetic nephropathy group were higher than those in the control group (P < 0.01) and the type 2 diabetes group (P < 0.01). Conclusion: PBG, FINS, and HbA1c are factors affecting the occurrence of diabetic nephropathy in patients with type 2 diabetes; thus, controlling the levels of PBG, FINS, and HbA1c can effectively prevent the occurrence of diabetic nephropathy in type 2 diabetes mellitus.

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2型糖尿病患者餐后血糖、空腹胰岛素和糖化血红蛋白水平与早期糖尿病肾病的关系

目的:探讨2型糖尿病患者餐后血糖(PBG)、空腹胰岛素(FINS)、糖化血红蛋白(HbA1c)水平与早期糖尿病肾病的关系。方法:选取我院2021年5月至2022年5月收治的96例2型糖尿病患者作为研究对象。根据尿白蛋白排泄率(UAER)将患者分为两组，2型糖尿病组53例(UAER < 30 ?g/min)，早期糖尿病肾病组43例(30 ?g/min)。UAER < 300g /min)。在87例健康患者中检测PBG、FINS和HbA1c水平。结果:早期糖尿病肾病组PBG、FINS、HbA1c水平均高于对照组(P < 0.01)和2型糖尿病组(P < 0.01)。结论:PBG、FINS、HbA1c是2型糖尿病患者糖尿病肾病发生的影响因素;因此，控制PBG、FINS和HbA1c水平可以有效预防2型糖尿病肾病的发生。

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抗癌研究

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