Significance of exosomes in Cardiology: Heralds of cardioprotection

Q Medicine

Revista Portuguesa De Pneumologia Pub Date : 2021-01-01 DOI:10.24875/ACME.M21000179

Miguel Arroyo-Campuzano, C. Zazueta

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引用次数: 1

Abstract

Los exosomas tienen un papel clave en la comunicacion intercelular. Debido a sus multiples interacciones, estas estructuras cumplen con el papel de «mensajeros» de forma dinamica, transportando su contenido a celulas blanco especificas y generando nuevas senales celulares. En este articulo se describen algunas de las proteinas, lipidos y acidos nucleicos que son transportados por estas vesiculas y que se han relacionado con cardioproteccion, con la finalidad de proporcionar informacion y generar interes sobre la relevancia de los exosomas como posibles blancos diagnosticos y terapeuticos. Exosomes have a key role in intercellular communication. Due to their multiple interactions, these structures fulfill the role of “messengers” in a dynamic way, transporting their content to target-specific cells and generating new cellular signals. This article describes some of the proteins, lipids and nucleic acids that are transported by these vesicles and that have been related to cardioprotection, in order to provide information and generate interest in the relevance of exosomes as possible diagnostic and therapeutic targets.

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外泌体在心脏病学中的意义:心脏保护的先兆

外泌体在细胞间通讯中起着关键作用。由于它们的多重相互作用，这些结构动态地发挥“信使”的作用，将其内容运输到特定的目标细胞并产生新的细胞信号。在这些囊泡中发现的蛋白质、脂类和核酸与心脏保护有关，目的是提供信息并引起人们对外泌体作为潜在诊断和治疗目标的相关性的兴趣。外泌体在细胞间通讯中起着关键作用。由于它们的多重相互作用，这些结构以一种动态的方式完成了“信使”的角色，将它们的内容传送到目标特定的细胞并产生新的细胞信号。本文描述了这些囊泡携带的一些与心脏保护有关的蛋白质、脂类和核酸，以便提供信息并引起人们对外泌体作为可能的诊断和治疗目标的相关性的兴趣。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Portuguesa De Pneumologia RESPIRATORY SYSTEM-

CiteScore

0.69

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Portuguese Journal of Pulmonology is the official journal of the Portuguese Society of Pulmonology (Sociedade Portuguesa de Pneumologia/SPP), with current editor Dr. Renato Sotto-Mayor. The aim of the journal is to publish scientific work which is either directly or indirectly related to the respiratory system. This work can range from original articles, revised articles, letters to the editor, editorials, reviews of international work, case studies, technical notes, studies, summaries of oral communications and posters presented at the Portuguese Society of Pulmonology’s Annual Congress and other work of recognised scientific merit.