Analysis of the Kazakh tribe Baiuly based on the distribution of the Y-chromosome haplogroups

IF 0.3 Q4 BIOLOGY

International Journal of Biology and Chemistry Pub Date : 2020-01-01 DOI:10.26577/ijbch.2020.v13.i2.10

O. A. Iksan, I. Kisselev, A. Garshin, L. Skvortsova, Zhassulan Zhaniyazov, M. A. Alpysbes, Charleston W. K. Chiang, L. Z. Musralina, G. Zhunussova, E. Khussainova

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Abstract

A haplogroup is a group of similar alleles that have a common ancestor in which a mutation has occurred, inherited by all descendants. Haplogroups, particularly from the Y-chromosome (Y-DNA), is widely used in population genetics and genetic genealogy, a science that studies the genetic history of mankind. Recent studies of the Y-chromosome of modern Kazakhs have demonstrated the diversity of the Kazakh gene pool. During the expedition carried out in 2014-2016, clinical material was collected from varios regions of Kazakhstan, representing samples of peripheral blood and buccal scrapings. All representatives of Kazakh nationality were familiarized with informed consent. In total 1623 respondents participated in the study, 169 of whom were representatives from Baiuly tribe of Junior zhuz. We analyzed the provided samples and found that the Baiuly is characterized by 10 haplogroups, the most prevailing of which is the C2 haplogroup (85%).

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基于y染色体单倍群分布的哈萨克族人分析

单倍群是一组相似的等位基因，它们有一个共同的祖先，发生了突变，并由所有后代遗传。单倍群，特别是来自y染色体(Y-DNA)的单倍群，广泛应用于群体遗传学和遗传谱系学，这是一门研究人类遗传历史的科学。最近对现代哈萨克人y染色体的研究已经证明了哈萨克人基因库的多样性。在2014-2016年进行的考察期间，从哈萨克斯坦的各个地区收集了临床材料，包括外周血和口腔刮痕样本。所有哈萨克族代表都熟悉知情同意。共有1623名受访者参与了这项研究，其中169名是Junior zhuz的Baiuly部落的代表。我们分析了所提供的样本，发现Baiuly具有10个单倍群，其中最常见的是C2单倍群(85%)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International Journal of Biology and Chemistry BIOLOGY-

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