ACTIVIDAD ANTIMICÓTICA DEL ACEITE ESENCIAL DE LAS HOJAS DE Minthostachys mollis (MUÑA) COMPARADO CON EL FLUCONAZOL EN CULTIVO DE Candida albicans

CIMEL Ciencia e Investigacion Medica Estudiantil Latinoamericana Pub Date : 2011-01-01 DOI:10.23961/CIMEL.2011.162.204

Katherine M Alcalá-Marcos, A. G. Alvarado-Gamarra, L. Alejandro-Paredes, Eduardo Huayané-Linares

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引用次数: 4

Abstract

Objective. - Demonstrate the antifungal effect of essential oil from leaves Minthostachys mollis (muna) compared to fluconazole in Candida albicans culture. Materials and Methods. - Experimental study. The antifungal effect was studied by measuring 80 inhibition zones divided into 5 groups using the Kirby-Bauer method. We used a clinical isolate of Candida albicans. The study groups were grouped as follow: “muna” 25% (GM25%), group “muna” 50% (GM50%), group “muna” 100% (GM100%), a positive control group (fluconazole) and a negative control group (mineral oil). Statistical analysis was performed using the Kruskal-Wallis and Dunn test using SPSS v.17.0. The level of significance was 0.05). Conclusion. - The essential oil from the leaves of Minthostachys mollis (100%) was more effective against Candida albicans than fluconazole, in addition, the antifungal effect of fluconazole was greater than Minthostachys mollis 25%, and was the same that Minthostachys mollis 50%.

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与氟康唑相比，薄荷叶精油在白色念珠菌培养中的抗真菌活性

目标。-在白色念珠菌培养中，与氟康唑相比，证明了薄荷叶精油的抗真菌效果。材料与方法。-实验研究。采用Kirby-Bauer法测定80个抑菌区，并将其分为5组，研究其抑菌效果。我们使用了一种临床分离的白色念珠菌。实验组分为:“穆纳”25% (GM25%)组、“穆纳”50% (GM50%)组、“穆纳”100% (GM100%)组、阳性对照组(氟康唑)和阴性对照组(矿物油)。使用SPSS v.17.0进行统计学分析，采用Kruskal-Wallis和Dunn检验。显著性水平为0.05)。结论。- 100%白念珠菌叶精油对白色念珠菌的抑菌效果优于氟康唑，氟康唑的抑菌效果大于白念珠菌25%，与白念珠菌50%的抑菌效果相同。

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CIMEL Ciencia e Investigacion Medica Estudiantil Latinoamericana

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10 weeks