SARCOMA SINOVIAL EN ADOLESCENTE. PRESENTACIÓN DE UN CASO Y REVISIÓN DE LA LITERATURA

Abstract

Synovial sarcoma (SS) is a mesenchymal spindle cell malignant tumor with areas of epithelial differentiation with variable grades of dysplasia. It represents the second most common malignant neoplasia in adolescents and young adults, after rhabdomyosarcoma. SS affects primarily the extremities, especially the lower limbs. According with surgical stages, the III / IVA stage has been associated with a much more precarious prognosis. For patients with unresectable disease at diagnosis (grade III), survival rates has been reported between 50 and 70%. The objective is to present a rare clinical case and understand the behavior of the tumor. 16 year old female patient with a medial and distal left arm mass, not mobile and painful on palpation. The Ultrasound reported soft tissue heterogeneous space-occupying lesion adjacent to 1/3 of the left humerus. The biopsy reported a Primary monophasic synovial sarcoma grade I ST III. Chemotherapy and radiotherapy were indicated for treatment, with satisfactory evolution. The patient is currently asymptomatic, without evidence of tumor activity. Synovial sarcoma is a rare tumor, the pathogenesis of SS is still unknown and there are not well-established risk factors. Its treatment is multidisciplinary and complex.