Complete versus culprit only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery disease

IF 0.2 4区医学 Q4 MEDICINE, GENERAL & INTERNAL

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI:10.2298/sarh220210002j

M. Jarakovic, M. Petrović, D. Ivanišević, Bojan Mihajlović, M. Kovacevic, I. Popov

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引用次数: 0

Abstract

Introduction/Objective. The optimal percutaneous coronary intervention (PCI) in patients with non-ST elevated myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) is still not clear. The aim of our study was to examine intrahospital and long term major adverse cardiovascular and cerebrovascular events (MACCE) in this group of patients. Methods. This retrospective study included 225 patients with NSTEMI and multivessel CAD treated with PCI at the Institute of Cardiovascular Diseases of Vojvodina. Three groups were formed: complete one stage PCI; complete multi stage PCI and culprit only PCI. We have analyzed intrahospital and one year follow up MACCE and mortality after three years in all three groups. Results. Complete one stage PCI was performed in 112 (49.8%), complete multi stage PCI in 70 (31.3%) and culprit only PCI in 43 (19.1%) of patients. Patients with multi stage complete PCI had lowest mortality in comparison with one stage and culprit only PCI, respectively, both intrahospital (0% vs. 0.9% or 20.9%, p < 0.0005) and after one year (0% vs. 2.7% or 30.2%, p < 0.0005) and three years (4.3% vs. 5.4% or 32.6%, p < 0.0005). There was no significant difference in other MACCE between groups both intrahospital and after one year. Conclusion. In our study, multi stage PCI significantly reduces intrahospital, one year and three years follow up mortality in patients with NSTEMI and multivessel CAD.

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非st段抬高型心肌梗死和多支冠状动脉疾病的完全血运重建与罪魁祸首血运重建

介绍/目标。非st段升高型心肌梗死(NSTEMI)合并多支冠状动脉疾病(CAD)患者的最佳经皮冠状动脉介入治疗(PCI)尚不清楚。本研究的目的是检查这组患者的院内和长期主要心脑血管不良事件(MACCE)。方法。本回顾性研究纳入伏伊伏丁那心血管疾病研究所接受PCI治疗的225例非stemi和多血管CAD患者。分为三组:完成一期PCI;完成多阶段PCI和罪犯仅PCI。我们分析了所有三组的院内和一年随访MACCE以及三年后的死亡率。结果。完成一期PCI 112例(49.8%)，完成多期PCI 70例(31.3%)，罪犯单纯PCI 43例(19.1%)。多期完全PCI患者的死亡率分别比单期和单纯罪魁祸首PCI患者最低，无论是院内(0%比0.9%或20.9%，p < 0.0005)、1年后(0%比2.7%或30.2%，p < 0.0005)和3年后(4.3%比5.4%或32.6%，p < 0.0005)。两组在院内和一年后的其他MACCE无显著差异。结论。在我们的研究中，多期PCI显著降低了NSTEMI合并多血管CAD患者的院内、1年和3年随访死亡率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Srpski arhiv za celokupno lekarstvo MEDICINE, GENERAL & INTERNAL-

CiteScore

0.40

自引率

50.00%

发文量

104

审稿时长

4-8 weeks

期刊介绍： Srpski Arhiv Za Celokupno Lekarstvo (Serbian Archives of Medicine) is the Journal of the Serbian Medical Society, founded in 1872, which publishes articles by the members of the Serbian Medical Society, subscribers, as well as members of other associations of medical and related fields. The Journal publishes: original articles, communications, case reports, review articles, current topics, articles of history of medicine, articles for practitioners, articles related to the language of medicine, articles on medical ethics (clinical ethics, publication ethics, regulatory standards in medicine), congress and scientific meeting reports, professional news, book reviews, texts for "In memory of...", i.e. In memoriam and Promemoria columns, as well as comments and letters to the Editorial Board. All manuscripts under consideration in the Serbian Archives of Medicine may not be offered or be under consideration for publication elsewhere. Articles must not have been published elsewhere (in part or in full).