Orofacial complaints and complications of chemotherapy

Q4 Medicine
C. Novaes, Rafaela Tristão e Silva, Ângela Mello Coelho, G. Fabri, Maria das Graças Afonso Miranda Chaves
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引用次数: 0

Abstract

effects, involving paraneoplastic mechanisms. Pain secondary to cancer therapy varies with the treatment modalities used: chemo-radiotherapy protocols are typically associated with painful mucositis and neurotoxicity. Surgical therapies often result in nerve and ABSTRACT Background: Oral complications of chemotherapy are sometimes unnoticed and if not treated, they can compromise patients’ health and quality of life. Methods: This study aimed to assess and characterize orofacial complaints and complications, and their impact on the oral-health-related quality of life in patients undergoing cancer chemotherapy. Results: We evaluated 28 patients with solid tumors undergoing chemotherapy, through a systematic orofacial evaluation. Eighteen patients (64.2%) developed oral complications during chemotherapy and xerostomia scored the highest incidence n = 14 (50%). About oral health data, gingival index revealed greater part of patients classified with moderate or severe gingival inflammation. The mean plaque index was 25.6%. The mean CPOD index was 15.48 and was worse in patients without oral complications. The patients presented higher plaque index and the oral health impact profile showed higher mean index in the patients group that developed oral complications. Conclusion: These data reinforce the crucial role of the dentist in the multidisciplinary team, with crucial suport in the diagnosis of oral complications. Thus, a specific assistance and relieve of patient’s complaints could impact positively on quality of life.
口腔面部疾病和化疗并发症
影响,涉及副肿瘤机制。癌症治疗后继发的疼痛因治疗方式的不同而不同:化疗-放疗方案通常与疼痛性粘膜炎和神经毒性有关。背景:化疗的口腔并发症有时会被忽视,如果不及时治疗,它们会危及患者的健康和生活质量。方法:本研究旨在评估和描述癌症化疗患者的口面部主诉和并发症,以及它们对口腔健康相关生活质量的影响。结果:我们评估了28例接受化疗的实体瘤患者,通过系统的口腔面部评估。化疗期间出现口腔并发症18例(64.2%),其中发生率最高的为口干症14例(50%)。关于口腔健康数据,牙龈指数显示大部分患者分为中度或重度牙龈炎症。平均斑块指数为25.6%。平均CPOD指数为15.48,无口腔并发症患者的CPOD指数更差。出现口腔并发症的患者斑块指数较高,口腔健康影响谱的平均指数也较高。结论:这些数据加强了牙医在多学科团队中的关键作用,对口腔并发症的诊断提供了重要支持。因此,一个具体的帮助和减轻病人的抱怨可以积极影响生活质量。
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来源期刊
Archive of Oncology
Archive of Oncology Medicine-Oncology
CiteScore
0.60
自引率
0.00%
发文量
5
审稿时长
12 weeks
期刊介绍: Archive of Oncology is an international oncology journal that publishes original research, editorials, review articles, case (clinical) reports, and news from oncology (medical, surgical, radiation), experimental oncology, cancer epidemiology, and prevention. Letters are also welcomed. Archive of Oncology is covered by Biomedicina Vojvodina, Biomedicina Serbica, Biomedicina Oncologica, EMBASE/Excerpta Medica, ExtraMED and SCOPUS.
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