Myokine Response to Resistance Exercise in Older Adults and the Similarities and Differences to Younger Adults: A Brief Narrative Review

S. Cornish, Dean M. Cordingley
{"title":"Myokine Response to Resistance Exercise in Older Adults and the Similarities and Differences to Younger Adults: A Brief Narrative Review","authors":"S. Cornish, Dean M. Cordingley","doi":"10.21926/obm.geriatr.2204206","DOIUrl":null,"url":null,"abstract":"Myokines are cytokines secreted from muscle during contraction and are implicated in autocrine, paracrine, and endocrine regulation of biological systems. It is postulated that myokines contribute to skeletal muscle adaptations in response to resistance exercise. Exercise, including resistance exercise, is an important factor in the management of maintaining skeletal muscle strength, mass, and function with aging. Sarcopenia is exacerbated with increased age and therefore, it is important to understand the potential underlying mechanisms whereby exercise may be beneficial in reducing the consequences of sarcopenia for older adults. Myokine secretion is one mechanism which is postulated to account for the benefits of exercise in aging muscle. The response of myokines to aerobic exercise in older adults have previously been reviewed; however, there is limited research focused on the response of myokines to resistance exercise. Therefore, the aim of this narrative review is to discuss the response of various myokines to an acute bout of resistance exercise and/or chronic resistance exercise training in older adults, compare the response between younger and older adults, and briefly outline the influence myokines may have on skeletal muscle adaptations.","PeriodicalId":74332,"journal":{"name":"OBM geriatrics","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"OBM geriatrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21926/obm.geriatr.2204206","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Myokines are cytokines secreted from muscle during contraction and are implicated in autocrine, paracrine, and endocrine regulation of biological systems. It is postulated that myokines contribute to skeletal muscle adaptations in response to resistance exercise. Exercise, including resistance exercise, is an important factor in the management of maintaining skeletal muscle strength, mass, and function with aging. Sarcopenia is exacerbated with increased age and therefore, it is important to understand the potential underlying mechanisms whereby exercise may be beneficial in reducing the consequences of sarcopenia for older adults. Myokine secretion is one mechanism which is postulated to account for the benefits of exercise in aging muscle. The response of myokines to aerobic exercise in older adults have previously been reviewed; however, there is limited research focused on the response of myokines to resistance exercise. Therefore, the aim of this narrative review is to discuss the response of various myokines to an acute bout of resistance exercise and/or chronic resistance exercise training in older adults, compare the response between younger and older adults, and briefly outline the influence myokines may have on skeletal muscle adaptations.
老年人抗阻运动的肌因子反应及其与年轻人的异同:简要回顾
肌因子是肌肉在收缩过程中分泌的细胞因子,与生物系统的自分泌、旁分泌和内分泌调节有关。据推测,肌因子有助于骨骼肌适应抵抗运动。运动,包括抗阻运动,是随着年龄增长保持骨骼肌力量、质量和功能的重要因素。骨骼肌减少症会随着年龄的增长而加剧,因此,了解运动可能有助于减少老年人骨骼肌减少症后果的潜在潜在机制非常重要。肌因子分泌是一种机制,它被认为可以解释运动对衰老肌肉的好处。肌因子对老年人有氧运动的反应已经被回顾过;然而,关于肌因子对抗阻运动的反应的研究有限。因此,这篇叙述性综述的目的是讨论各种肌因子对老年人急性抵抗运动和/或慢性抵抗运动训练的反应,比较年轻人和老年人的反应,并简要概述肌因子对骨骼肌适应的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信