Epilepsy as an initial factor of the clinical presentation of arteriovenous malformations of the brain - natural history and risk factors

Marina Radosavljević, R. Repac, M. Nikolic, B. Djoric, M. Janicijevic, P. S. Matic, D. Scepanovic, T. Jovanovic, S. Milić, M. Tasic
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Abstract

We present the results of treatment of 15 patients with brain arteriovenous malformation initially presented by epilepsy in Neurosurgery, Clinical Center of Serbia in Belgrade, in the period 2004-2010 year. Results: Most of the patients had a grand mall type of epilepsy, 14 of them, while one was present petit mall epilepsy. The attacks are manifested individually in 14, and in 1 case series. Response to treatment was good in 11 and 4 patients with refractory. In 26.7% of cases, seizures alternated with bleeding. Anatomical features of malformations did not show a significant difference in the predisposition to epilepsy treatment response . Conclusion: Good control of epilepsy by medication supports the view that there is no need for urgent surgical treatment of brain AVM so we can generally conclude that brain AVM in relation to a wide range of neurosurgical patients are in benign lesions, which requires patience and good workmanship and strategic therapeutic approach.
癫痫作为脑动静脉畸形临床表现的初始因素-自然史和危险因素
我们介绍了2004-2010年期间在贝尔格莱德塞尔维亚临床中心神经外科治疗的15例最初由癫痫引起的脑动静脉畸形患者的治疗结果。结果:14例患者以大小型癫痫为主,1例为小小型癫痫。这些攻击分别在14个案例中表现出来,在1个案例系列中表现出来。治疗效果良好11例,难治性4例。在26.7%的病例中,癫痫发作与出血交替发生。畸形的解剖特征在癫痫治疗反应的易感性上没有显着差异。结论:药物对癫痫的良好控制支持脑AVM不需要紧急手术治疗的观点,因此我们可以普遍认为,脑AVM涉及广泛的神经外科患者是良性病变,需要耐心和良好的工艺和策略治疗方法。
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