Primary Prevention of Venous Thromboembolism: Current State

Q4 Medicine

Flebologiya Pub Date : 2022-01-01 DOI:10.17116/flebo202216021164

D. V. Frolov, V. Petrov, G. Sukhanova, D. V. Linchenko, A.E. Nalesnyi, Y. Dyachkova

引用次数: 2

Abstract

The problem of primary prevention of venous thromboembolism (VTE) is currently extremely important throughout the world for various specialists, especially in general surgery, orthopedics, intensive care and therapy. Among all preventive measures, special attention should be paid to anticoagulation in acute phase of disease at the in-hospital stage and early after discharge. This review is devoted to dosage, regimen and duration of anticoagulation depending on the risk of VTEC, efficacy and safety of parenteral and oral anticoagulants. Criteria for anticoagulation dose increment or prolongation of therapy to the outpatient stage are also proposed: high and extremely high level of D-dimer with additional risk factors of VTEC, obesity, reduced motor activity in postoperative period, previous VTEC, additional Caprini scores due to a widespread new coronavirus infection. Conclusions about the need to revise the guidelines on primary prevention of VTEC are made.

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静脉血栓栓塞的一级预防：现状

静脉血栓栓塞(VTE)的一级预防问题目前对世界各地的各种专家来说都非常重要，特别是在普外科、骨科、重症监护和治疗方面。在所有预防措施中，应特别注意疾病急性期、住院期和出院后早期的抗凝治疗。本文综述了基于VTEC风险的抗凝剂量、方案和持续时间，以及肠外和口服抗凝剂的有效性和安全性。抗凝剂量增加或延长治疗至门诊阶段的标准也被提出:高和极高水平的d -二聚体并伴有VTEC、肥胖、术后运动活动减少、既往VTEC、由于广泛的新型冠状病毒感染而增加的capriini评分。结论是有必要修订VTEC一级预防指南。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Flebologiya Medicine-Hematology

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Journal of Venous Disorders is a quarterly peer-reviewed medical journal. The journal highlights the key issues of prophylaxis, diagnostics and treatment of the entire spectrum of venous system diseases and their complications including acute (deep vein thrombosis, pulmonary embolism, superficial thrombophlebitis) and chronic (varicose veins, post-thrombotic syndrome, chronic venous insufficiency) pathologies as well as various lymphatic lesions (lymphedema, etc.). The new edition will encompass the whole range of topical issues including recent achievements of domestic and foreign researchers, applications of innovative technologies in the clinical practice, reviews of the literature, lectures, and results of original investigations: all that can be of interest for phlebologists, vascular surgeons, other medical specialists dealing with venous pathology in their practical work. The journal was established in 2007. The only Russian journal that reflecting a broad range of problems in diagnosis, treatment and prevention of acute and chronic venous diseases.