Platelet-Rich Plasma for Degenerative Spine Disease: A Brief Overview.

IF 1.2 Q3 SURGERY
Spine Surgery and Related Research Pub Date : 2023-07-06 eCollection Date: 2024-01-27 DOI:10.22603/ssrr.2023-0079
Sotirios Apostolakis, Stylianos Kapetanakis
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引用次数: 0

Abstract

Background: The emergence of novel minimally invasive techniques has opened new horizons for the management of degenerative diseases of the spine. Platelet-rich plasma (PRP) has gained considerable attention through its applications in various pathologies. In the present review, an overview of the science behind the application of PRP is provided, ultimately focusing on the clinical trials that may render it a useful tool in the hands of spine surgeons in the future.

Methods: A review of the available literature is conducted, focusing on its existing clinical and experimental applications with a particular interest in the degenerative diseases of the spine.

Results: In terms of the degenerative diseases of the spine, initial studies suggest that it is a safe and effective method that could change the practice of spinal cord medicine in the years to come. The available studies demonstrate that besides being minimally invasive, causing less discomfort than that of surgery, it provides longer lasting improvement than standard pharmaceutical interventions.

Conclusions: PRP is an emerging and promising biodrug for the treatment of patients with spinal pain. PRP has demonstrated some promising qualities; however, careful consideration of its indications of use and strict protocols of application need to be established before widespread clinical induction.

富血小板血浆治疗脊柱退行性疾病:简要概述。
背景:新型微创技术的出现为脊柱退行性疾病的治疗开辟了新天地。富血小板血浆(PRP)因其在各种病症中的应用而备受关注。本综述概述了 PRP 应用背后的科学原理,并最终关注临床试验,这些试验可能会使 PRP 成为脊柱外科医生手中的有用工具:方法:对现有文献进行回顾,重点关注其现有的临床和实验应用,尤其是脊柱退行性疾病:就脊柱退行性疾病而言,初步研究表明这是一种安全有效的方法,可能在未来几年内改变脊髓医学的实践。现有的研究表明,除了微创、造成的不适比手术少之外,它还能比标准药物干预提供更持久的改善:结论:PRP 是一种治疗脊柱疼痛患者的新兴生物药物,前景广阔。PRP 已显示出一些有前途的特性,但在广泛临床应用之前,还需要仔细考虑其使用适应症和严格的应用规程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.80
自引率
0.00%
发文量
71
审稿时长
15 weeks
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