Bioactive Constituents from the Twigs of Sonneratia alba

Q3 Multidisciplinary

Walailak Journal of Science and Technology Pub Date : 2011-12-10 DOI:10.2004/WJST.V1I1.196

Kanchuree Chaiyadej, Hathaichanok Wongthap, S. Vadhanavikit, K. Chantrapromma

引用次数: 7

Abstract

Three pentacyclic triterpenoids: lupeol [1], oleanolic acid [2], and betulinic acid [3] were isolated from the twigs of Sonneratia alba together with 2,6-dimethoxy-p-benzoquinone [4], a mixture of stigmasterol [5] and b-sitosterol [6]. Their structures were elucidated by analyses of their 1D and 2D NMR, and their physical and spectral data were compared with those reported in the literature. Amongst these isolates, compounds [2,3] exhibit antimycobacterial activity with MIC values of 25 and 50 mg/ml respectively. In addition, compound [4] exhibited antimalarial activity against P. falciparum with an IC50 value of 3.08 mg/ml.

查看原文本刊更多论文

海桑幼枝的生物活性成分研究

从海桑枝条中分离得到三个五环三萜:芦皮醇[1]、齐墩果酸[2]、白桦酸[3]和2,6-二甲氧基-对苯醌[4]，即豆甾醇[5]和b-谷甾醇[6]的混合物。通过对它们的一维和二维核磁共振分析，对它们的结构进行了鉴定，并将它们的物理和光谱数据与文献报道的数据进行了比较。在这些分离物中，化合物[2,3]表现出抗真菌活性，MIC值分别为25和50 mg/ml。化合物[4]对恶性疟原虫具有抗疟活性，IC50值为3.08 mg/ml。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Walailak Journal of Science and Technology Multidisciplinary-Multidisciplinary

CiteScore

0.80

自引率

0.00%

发文量

审稿时长

24 weeks

期刊介绍： The Walailak Journal of Science and Technology (Walailak J. Sci. & Tech. or WJST), is a peer-reviewed journal covering all areas of science and technology, launched in 2004. It is published 12 Issues (Monthly) by the Institute of Research and Innovation of Walailak University. The scope of the journal includes the following areas of research : - Natural Sciences: Biochemistry, Chemical Engineering, Chemistry, Materials Science, Mathematics, Molecular Biology, Physics and Astronomy. -Life Sciences: Allied Health Sciences, Biomedical Sciences, Dentistry, Genetics, Immunology and Microbiology, Medicine, Neuroscience, Nursing, Pharmaceutics, Psychology, Public Health, Tropical Medicine, Veterinary. -Applied Sciences: Agricultural, Aquaculture, Biotechnology, Computer Science, Cybernetics, Earth and Planetary, Energy, Engineering, Environmental, Food Science, Information Technology, Meat Science, Nanotechnology, Plant Sciences, Systemics