CONGRESS COVERAGE: Obese Children have a Quadrupled Risk of Becoming Hypertensive Adults in Comparison to Children with Normal Weight

Q4 Medicine
E. Ganotakis, A. Papagianni, V. Athyros
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Abstract

A few days ago (Sept 12, 2013) the results of a large prospective study that included 1,117 healthy children who were followed up for 27 years were presented in the American Heart Association (AHA) High Blood Pressure Research Scientific Sessions in New Orleans [1]. The aim was to record the development of obesity in childhood and to investigate the incidence of arterial hypertension (HTN) in adults that were obese or overweight children [1]. The original cohort was established in 1986, and consisted of 1,117 healthy children (47% male), recruited from schools in Indianapolis, Indiana, USA (mean age 12 years). During follow-up, blood pressure (BP), height, and weight were measured twice a year. Body mass index (BMI) was calculated from height and weight; weight status was determined by age and sexadjusted BMI percentile values (BMI %). Subjects were classified as normal weight, overweight (BMI% 85% and < 95%), or obese (BMI% 95%) of BMI distribution of the entire cohort [1]. The above revealed that 765 (68%) had normal weight, 176 (16%) were overweight, and 176 (16%) were obese [1]. The rate of adult HTN was higher for those classified as overweight or obese as children (14% and 26% respectively, p = <0.0001). Children classified as overweight or obese had double and quadruple the risk of having HTN in adulthood, respectively, as compared to normal weight children [odds ratio (OR) = 2.2; 95% confidence interval (CI) = 1.3 to 3.6, OR = 4.4; 95% CI = 2.8 to 6.9, respectively] [1]. It has also been shown that children who had one or more high BP readings are 3 times more likely to develop HTN as adults. Using the same pool of Indianapolis kids, researchers found that the rate of high BP during adulthood was 8.6% for children who didn't have a high BP reading when they were young. That rate jumped to 18% for adults who had at least 1 high reading as a kid, and 35% for adults who had 2 or more high readings as children [1]. This study highlights the need for pediatricians to regularly check BP
国会报道:肥胖儿童成人患高血压的风险是正常体重儿童的四倍
几天前(2013年9月12日),在新奥尔良举行的美国心脏协会(AHA)高血压研究科学会议上发表了一项大型前瞻性研究的结果,该研究对1117名健康儿童进行了27年的随访。目的是记录儿童时期肥胖的发展情况,并调查肥胖或超重儿童的成人动脉高血压(HTN)的发病率。最初的队列建立于1986年,包括从美国印第安纳州印第安纳波利斯的学校招募的1,117名健康儿童(47%为男性)(平均年龄12岁)。随访期间,每年测量两次血压、身高和体重。体重指数(BMI)由身高和体重计算;体重状况由年龄和性别调整后的BMI百分位数(BMI %)决定。受试者按整个队列BMI分布[1]分为正常体重、超重(BMI% 85%和< 95%)和肥胖(BMI% 95%)。其中体重正常765人(68%),超重176人(16%),肥胖176人(16%)。成人HTN的发生率在儿童超重或肥胖人群中较高(分别为14%和26%,p = <0.0001)。与体重正常的儿童相比,超重或肥胖儿童成年后患HTN的风险分别为两倍和四倍[优势比(or) = 2.2;95%置信区间(CI) = 1.3 ~ 3.6, OR = 4.4;95% CI = 2.8 ~ 6.9]。研究还表明,有一次或多次高血压读数的儿童成年后患HTN的可能性是常人的3倍。研究人员对印第安纳波利斯的同一群孩子进行了研究,发现那些年轻时血压读数不高的孩子成年后血压升高的比例为8.6%。在儿童时期至少有一次高阅读量的成年人中,这一比例跃升至18%,在儿童时期有两次或两次以上高阅读量的成年人中,这一比例跃升至35%。这项研究强调了儿科医生定期检查血压的必要性
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来源期刊
Open Hypertension Journal
Open Hypertension Journal Medicine-Cardiology and Cardiovascular Medicine
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