Biomat _dBase: A Database on Biomaterials

Bano Subia, Sunandan Mukherjee, R. Bahadur, V. Correlo, L. ReisRui, R. Sabarinathan, K. Sekar, S. Kundu
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引用次数: 5

Abstract

Biomaterial science provides a platform for the development of bio-artificial implants. Growth or development of engineered tissues for the purpose of repairing, restoring and enhancing the function of a damaged tissue or organ needs designed biomaterials. The most studied tissue engineering strategy consists on using cells growth factors and temporary three-dimensional (3D) porous scaffolds. 3D scaffolds play a very important role in the success of tissue engineering and regenerative medicine. They provide structural support for cells to proliferate and maintain their differentiated phenotype and permit the convenient delivery of cells into the patients. Several features of scaffold can influence the cell growth and its functions. The artificial extracellular matrices can be produced from different biomaterials including ceramics, natural or synthetic polymers and composites. Recent discoveries and innovations in this emerging field adopt varieties of techniques ranging from biotechnology to material science and nanotechnology. The result is a huge amount of data. To maintain and keep updated, this would not be an easy task. New advances in computers and information technology help to create and organize the databases quite easy. Their contents can easily be accessed, managed and updated. A WWW interface benefits the users to search the different types of data based on the types of biomaterials, their abundance, structure and applications. This provides the scope and archive of information on this emerging field of biomaterials to the global scientific community. The database is freely accessible through http://dbbiomat.iitkgp.ernet.in.
Biomat _dBase:一个生物材料数据库
生物材料科学为生物人工植入物的发展提供了平台。为了修复、恢复和增强受损组织或器官的功能,工程组织的生长或发育需要设计的生物材料。研究最多的组织工程策略是使用细胞生长因子和临时三维多孔支架。三维支架在组织工程和再生医学的成功中起着非常重要的作用。它们为细胞增殖和维持其分化表型提供结构支持,并允许细胞方便地进入患者体内。支架的一些特性会影响细胞的生长及其功能。人工细胞外基质可以由不同的生物材料制成,包括陶瓷、天然或合成聚合物和复合材料。这一新兴领域的最新发现和创新采用了从生物技术到材料科学和纳米技术的各种技术。其结果是大量的数据。要维护和保持更新,这不是一件容易的事。计算机和信息技术的新进展有助于创建和组织数据库。它们的内容可以很容易地访问、管理和更新。基于生物材料的种类、丰度、结构和应用,使用户能够搜索到不同类型的数据。这为全球科学界提供了这一新兴生物材料领域的范围和信息档案。该数据库可通过http://dbbiomat.iitkgp.ernet.in免费访问。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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