Anti-Inflammatory Activity of Ethanolic Extract of Flowers Hymenocallis littoralis (Jacq.) Salisb. By HRBC Membrane Stabilization Method

R. Karthikeyan, O. SaiKoushik, P. Srinivasababu, Jayendra Chunduru
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引用次数: 5

Abstract

Hymenocallis littoralis (Jacq.) Salisb. (Amaryllidaceae) is commonly referred as Beach spider lily, is a medicinal plant and ornamental, conventionally used for wound healing. It is used as an emetic and has shown anti-viral, anti-neoplastic and cytotoxic properties. To treat blemishes and freckles the plant is used as folk remedy. The aim of this research is to explore the antiinflammatory potential of this selected plant material. Using inhibition of protein denaturation method crude extract of its flowers were subjected for in vitro antiinflammatory activity. The successive ethanol extract have shown potent anti-inflammatory activity by HRBC membrane stabilization method with 83.46% and 84.72% for 100 and 500 μg/ml, respectively. Significant antiinflammatory activity by HRBC membrane stabilization was shown by crude ethanol extarct. All the concentrations prepared were paving dose dependent anti-inflammatory activity.
滨海膜瓣花乙醇提取物的抗炎活性研究Salisb。HRBC膜稳定法
滨海膜虫(Jacq.)Salisb。(Amaryllidaceae)通常被称为沙滩蜘蛛百合,是一种药用植物和观赏植物,传统上用于伤口愈合。它被用作催吐剂,具有抗病毒、抗肿瘤和细胞毒性。为了治疗瑕疵和雀斑,这种植物被用作民间疗法。本研究的目的是探索这种选定的植物材料的抗炎潜力。采用抑制蛋白变性法对其花粗提物进行体外抗炎活性研究。经HRBC膜稳定法测定,100 μg/ml和500 μg/ml连续乙醇提取物的抗炎活性分别为83.46%和84.72%。粗乙醇提取物对HRBC膜稳定具有显著的抗炎活性。各制备浓度均呈现剂量依赖性抗炎活性。
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