A Comparative Study of Stigma, Quality of Life and Family Burden in Patients of Schizophrenia and Obsessive-Compulsive Disorder

P. Das, Smarajit Roy, Saurav Das
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引用次数: 3

Abstract

Objectives: Schizophrenia (SCH) is characterized by perceptual-disability with disintegrated memory/thinking-ability. Obsessive-compulsive-disorder (OCD) defines the unwanted dependence on some thought and repetitive-behaviour. Ritualistic and obsessive behaviours are the characters in OCD patients. Stigma and the quality-oflife (QOL) associated to either condition is less studied in relation to their caregiver’s role and responsibility. In the current study, this has been extensively studied. Methods: The individuals for this study were selected by consecutive sampling from patient (30-schizophrenia/30-OCD with their caregivers) coming to the OPD of the Institute of Psychiatry-Diagnosed by two consultant psychiatrists by applying ICD- 10. The severity of OCD was tested by using Yale-Brown Obsessive-Compulsive-Scale (Y-BOCS) and that of schizophrenia was evaluated by Positive and Negative-Syndrome- Scale (PANSS). Family Interview Schedule and WHO QOL-BREF were analyzed. Results: In both genders, SCH is 2-3-fold abundant than OCD. It is also higher in urban, but OCD is higher in rural-people. In employed-person and in nuclear-family OCD is higher whereas, SCH is higher in case of joint family and in >10th std. person. Income/ age and age-of-onset of disease were not a determining factor for both diseases. Symptoms of SCH on PANSS of total Psycho-pathological individuals were significantly higher than total positive or total negative score. The total QOL was better in OCD patients than schizophrenic patients (p value=0.000**). Conclusions: It is demonstrated that significant positive correlation between positive syndromes of Schizophrenia and stigma (r=-0.564, P=0.001) which means severity of various positive symptoms of schizophrenia shows high stigma positive syndrome with negative correlation with all domain of QOL.
精神分裂症与强迫症患者的耻辱感、生活质量及家庭负担的比较研究
目的:精神分裂症(SCH)以知觉障碍和记忆/思维能力解体为特征。强迫症(OCD)定义了对某些想法和重复行为的不必要依赖。仪式和强迫行为是强迫症患者的特征。与这两种疾病相关的耻辱感和生活质量(QOL)与照顾者的角色和责任之间的关系研究较少。在目前的研究中,这已经得到了广泛的研究。方法:本研究采用连续抽样的方法,从两名精神科顾问使用ICD- 10软件到精神病学诊断研究所门诊就诊的患者(30-精神分裂症/30-强迫症及其护理者)中选择个体。强迫症的严重程度采用耶鲁-布朗强迫症量表(Y-BOCS),精神分裂症的严重程度采用阳性和阴性症状量表(PANSS)。对家庭访谈时间表和WHO QOL-BREF进行分析。结果:在两性中,SCH比OCD多2-3倍。城市人群的强迫症发生率也更高,但农村人群的强迫症发生率更高。在受雇者和核心家庭中,强迫症较高,而在联合家庭和10岁以上的家庭中,自闭症较高。收入/年龄和发病年龄不是这两种疾病的决定性因素。精神病理总个体在PANSS上的SCH症状显著高于总阳性和总阴性得分。强迫症患者总生活质量优于精神分裂症患者(p值=0.000**)。结论:精神分裂症阳性综合征与柱头呈显著正相关(r=-0.564, P=0.001),精神分裂症各种阳性症状的严重程度均表现为高柱头阳性综合征,与生活质量各域呈负相关。
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