First Demonstration of the Effects of Remote Per- and Postconditioning onIschemia and Reperfusion Induced Hepatic Injury

Abstract

Ischemia and reperfusion is a very frequently phenomenon that is presented in many clinical situations like in liver transplantation as well as in traumatic situation of these organs.One way of minimizing this injury is the remote ischemic perconditioning, described in myocardial ischemia, in which brief nonlethal cycles of ischemia and reperfusion of the arm or leg are applied remotely during index ischemia. Therefore, this current study aims to compare the effects of perconditioning and postconditioning on injury of ischemia and reperfusion in the liver.