{"title":"Water Absorption of Chitosan, Collagen and Chitosan/Collagen Blend Membranes Exposed to Gamma-ray Irradiation","authors":"F. Lukitowati, D. J. Indrani","doi":"10.22034/IJPS.2018.32049","DOIUrl":null,"url":null,"abstract":"TThis study investigated the water absorption of chitosan, collagen, and chitosan/collagen blend membranes exposed to gamma-ray irradiation. These membranes were produced via the solvent evaporation method. All membranes then underwent irradiation at 15 or 25 kGy gamma-ray doses, while membranes without irradiation were used as controls. After immersing the membranes in distilled water for up to 180 min, water absorption was determined by calculating the percentage weight increase. The results showed changes in the water absorption curves with differing membranes and irradiation doses. However, after 60 min, all of the water absorption curves plateaued. With respect to membrane type, chitosan membranes exhibited the highest water absorption, the blend displayed the lowest, and collagen was in the mid range. With the use of higher radiation doses, chitosan membranes displayed lower water absorption, which was also true of the blend but not collagen membranes. To conclude, the water absorption of chitosan, collagen, and chitosan/collagen blend membranes with and without gamma-ray irradiation initially increased steadily and then plateaued. The water absorption values of the irradiated blend membranes were the lowest; however, the values were relatively steady.","PeriodicalId":14582,"journal":{"name":"Iranian Journal of Pharmaceutical Sciences","volume":"14 1","pages":"57-66"},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22034/IJPS.2018.32049","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 10
Abstract
TThis study investigated the water absorption of chitosan, collagen, and chitosan/collagen blend membranes exposed to gamma-ray irradiation. These membranes were produced via the solvent evaporation method. All membranes then underwent irradiation at 15 or 25 kGy gamma-ray doses, while membranes without irradiation were used as controls. After immersing the membranes in distilled water for up to 180 min, water absorption was determined by calculating the percentage weight increase. The results showed changes in the water absorption curves with differing membranes and irradiation doses. However, after 60 min, all of the water absorption curves plateaued. With respect to membrane type, chitosan membranes exhibited the highest water absorption, the blend displayed the lowest, and collagen was in the mid range. With the use of higher radiation doses, chitosan membranes displayed lower water absorption, which was also true of the blend but not collagen membranes. To conclude, the water absorption of chitosan, collagen, and chitosan/collagen blend membranes with and without gamma-ray irradiation initially increased steadily and then plateaued. The water absorption values of the irradiated blend membranes were the lowest; however, the values were relatively steady.
期刊介绍:
Iranian Journal of Pharmaceutical Sciences (IJPS) is an open access, internationally peer-reviewed journal that seeks to publish research articles in different pharmaceutical sciences subdivisions: pharmacology and toxicology, nanotechnology, pharmaceutics, natural products, biotechnology, pharmaceutical chemistry, clinical pharmacy and other pharmacy related topics. Each issue of the journal contents 16 outstanding research articles in area of pharmaceutical sciences plus an editorial written by the IJPS editors on one of the most up to date advances topics in pharmacy. All articles published by IJPS would be permanently accessible online freely without any subscription charges. Authors of the published articles have granted the right to use and disseminate their article to third parties.