ADMINISTRATION IN EXTREME CONDITIONS OF MEDICAMENTS BASED ON NICOTINIC ACID AND ITS DERIVATIVES

Abstract

The literary review encompasses the experimental and clinical evidence of the potency of Russian medicaments nicotinoyl gamma-aminobutyric acid (picamilon), hydroxyzine nicotinoyl glutamate calcium (ampasse), and combineddrug cytoflavin containing nicotinic acid and its derivatives in extreme conditions. Analysis shows that these medicaments and nicotinic acid derivatives protect tangibly from acute and chronic hypoxia of varying genesis, hypo- and hyperthermia, hypokinesia etc. To increase potency and safety of medical care after exposure to extreme factors the search for other nicotinic acid derivatives should be furthered.