Species-specific antigens of Streptococcus pneumoniae as an outlook for new diagnostic systems

Q4 Medicine

Infektsionnye Bolezni Pub Date : 2021-01-01 DOI:10.20953/1729-9225-2021-4-73-78

N. G. Sidorov, A. Poddubikov

引用次数: 0

Abstract

Infections caused by Streptococcus pneumoniae have always been a significant challenge for healthcare worldwide. Existing diagnostic methods are not always able to identify capsule-free forms of pneumococci or optochin-resistant strains that also play an important role in the development of pneumococcal infections. Such limitations of diagnostic procedures necessitate the development of serotype-independent tests. This review focuses on the antigenic structure of Streptococcus pneumoniae, specific characteristics of teichoic and lipoteichoic acids, and analyzes currently available diagnostic methods. We evaluated the utility of species-specific antigens as candidates for new diagnostic systems. Key words: Streptococcus pneumoniae, teichoic acid, lipoteichoic acid, choline binding proteins, species-specific antigens

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本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Infektsionnye Bolezni Medicine-Infectious Diseases

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： The journal publishes original research works, reviews of literature, lectures, methodological recommendations, clinical observations. Main topics: problems of etiology, pathogenesis, clinical manifestations of infectious diseases, new techniques and methods of their diagnosis, prevention and treatment; special attention is paid to the problems of antibacterial and antiviral therapy, the use of immunoglobulins and interferons, and also to intensive therapy of critical states. The journal is in the List of leading scientific journals and periodicals of the Supreme Attestation Committee, where the principal results of doctoral dissertations should be published.