Current concept of cerebral dysfunction in COVID-19 patients

Q4 Medicine

Infektsionnye Bolezni Pub Date : 2021-01-01 DOI:10.20953/1729-9225-2021-3-109-115

V. Maleev, S.M. Vedinov, V. Gorodin

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引用次数: 0

Abstract

There have been very few studies analyzing neuropsychiatric aspects of COVID-19 and the impact of somatic aspects of infection on the development of transient or persistent deficits in higher cerebral functions. This is primarily due to the small number of specialists in neuropsychiatry who work with COVID-19 patients and also because the healthcare system is primarily focused on the diagnosis and treatment of the somatic pathology. In this review, we analyzed the studies assessing the neuropsychiatric aspects of COVID-19 with a focus on possible somatic predictors of their development. We discuss neuropsychiatric manifestations of cerebral dysfunction in patients with new coronavirus infection and provide a description of the dynamics of symptom development and regression. We also cover the issues related to stress resistance of healthcare professionals working with COVID-19 patients. Particular attention is paid to the treatment of COVID-associated cerebral dysfunction and therapeutic options of neuroprotection. Key words: new coronavirus infection, COVID-19, delirium, postcovid neuropsychiatric syndrome, cognitive deficit, suicidal tendencies, encephalopathy

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COVID-19患者脑功能障碍的最新概念

目前很少有研究分析COVID-19的神经精神方面以及感染的躯体方面对高级脑功能发生短暂或持续性缺陷的影响。这主要是由于与COVID-19患者一起工作的神经精神病学专家数量较少，也因为医疗保健系统主要侧重于躯体病理的诊断和治疗。在这篇综述中，我们分析了评估COVID-19神经精神方面的研究，重点关注其发展的可能的躯体预测因素。我们讨论了新型冠状病毒感染患者脑功能障碍的神经精神表现，并提供了症状发展和消退的动态描述。我们还介绍了与COVID-19患者一起工作的医疗保健专业人员的抗压力性相关问题。特别关注与covid - 19相关的脑功能障碍的治疗和神经保护的治疗选择。关键词:新型冠状病毒感染，COVID-19，谵妄，covid后神经精神综合征，认知缺陷，自杀倾向，脑病

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来源期刊

Infektsionnye Bolezni Medicine-Infectious Diseases

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： The journal publishes original research works, reviews of literature, lectures, methodological recommendations, clinical observations. Main topics: problems of etiology, pathogenesis, clinical manifestations of infectious diseases, new techniques and methods of their diagnosis, prevention and treatment; special attention is paid to the problems of antibacterial and antiviral therapy, the use of immunoglobulins and interferons, and also to intensive therapy of critical states. The journal is in the List of leading scientific journals and periodicals of the Supreme Attestation Committee, where the principal results of doctoral dissertations should be published.