Taste disorders in children treated for hemoblastosis: analysis of prevalence and possible causes

Q3 Medicine

Voprosy Detskoi Dietologii Pub Date : 2022-01-01 DOI:10.20953/1727-5784-2022-4-61-69

A. Vashura, E. Zhukovskaya, T. Kovtun, Yuri Obukhov, S. Lukina, A. Khavkin

{"title":"Taste disorders in children treated for hemoblastosis: analysis of prevalence and possible causes","authors":"A. Vashura, E. Zhukovskaya, T. Kovtun, Yuri Obukhov, S. Lukina, A. Khavkin","doi":"10.20953/1727-5784-2022-4-61-69","DOIUrl":null,"url":null,"abstract":"Objective. To study the structure of taste disorders and possible risk factors of their development in children after the end of hemoblastosis treatment. Patients and methods. This retrospective study included data on 54 children who underwent rehabilitation in the Treatment and Rehabilitation Research Center “Russkoe Pole” of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology. A comparison group was formed of 216 patients with hemoblastosis. Taste sensitivity analysis method: GOST (All-Union State Standard) ISO 3972-2014 (sweet, salty, bitter, sour tastes). Results of the dental examination and consultation with a neurologist, time after the end of treatment, and body composition (body fat and lean body mass) were analyzed. Results. It was found that 64.8% of children had nutritional disorders, 48.1% – excess body fat, 7.5% – severe dysgeusia, 24.1% – impaired sensitivity to three tastes, 24.1% – to two tastes, and 44.3% – to one taste. Ageusia to bitter taste (26%) and hypergeusia to sour taste (20%) were the most common. No significant correlation with the time after the end of treatment was obtained. Conclusion. Statistically significant differences were found between the study group and the comparison group depending on the investigated risk factors. To obtain highly significant results, it is advisable to conduct prospective studies in larger patient groups. Key words: children, taste disorders, malignant neoplasms, hemoblastosis, nutritional status, toxic neuropathy, dental status","PeriodicalId":53444,"journal":{"name":"Voprosy Detskoi Dietologii","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Voprosy Detskoi Dietologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20953/1727-5784-2022-4-61-69","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Objective. To study the structure of taste disorders and possible risk factors of their development in children after the end of hemoblastosis treatment. Patients and methods. This retrospective study included data on 54 children who underwent rehabilitation in the Treatment and Rehabilitation Research Center “Russkoe Pole” of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology. A comparison group was formed of 216 patients with hemoblastosis. Taste sensitivity analysis method: GOST (All-Union State Standard) ISO 3972-2014 (sweet, salty, bitter, sour tastes). Results of the dental examination and consultation with a neurologist, time after the end of treatment, and body composition (body fat and lean body mass) were analyzed. Results. It was found that 64.8% of children had nutritional disorders, 48.1% – excess body fat, 7.5% – severe dysgeusia, 24.1% – impaired sensitivity to three tastes, 24.1% – to two tastes, and 44.3% – to one taste. Ageusia to bitter taste (26%) and hypergeusia to sour taste (20%) were the most common. No significant correlation with the time after the end of treatment was obtained. Conclusion. Statistically significant differences were found between the study group and the comparison group depending on the investigated risk factors. To obtain highly significant results, it is advisable to conduct prospective studies in larger patient groups. Key words: children, taste disorders, malignant neoplasms, hemoblastosis, nutritional status, toxic neuropathy, dental status

查看原文本刊更多论文

治疗成血细胞病的儿童味觉障碍:患病率及可能原因分析

目标。目的探讨造血干细胞病治疗结束后儿童味觉障碍的结构及其可能的危险因素。患者和方法。这项回顾性研究包括54名在Dmitry Rogachev国家儿童血液学、肿瘤学和免疫学医学研究中心“Russkoe Pole”治疗和康复研究中心接受康复治疗的儿童的数据。以216例造血增生患者为对照组。味觉灵敏度分析方法:GOST (All-Union State Standard) ISO 3972-2014(甜、咸、苦、酸的味道)。分析患者牙科检查和神经科会诊的结果、治疗结束后的时间、体成分(体脂和瘦体重)。结果。结果发现，64.8%的儿童患有营养障碍，48.1%的儿童患有体脂过多，7.5%的儿童患有严重的语言障碍，24.1%的儿童患有三种味道的敏感性受损，24.1%的儿童患有两种味道的敏感性受损，44.3%的儿童患有一种味道的敏感性受损。苦味(26%)和酸味(20%)是最常见的。与治疗结束后的时间无显著相关。结论。根据调查的危险因素，研究组和对照组之间存在统计学上的显著差异。为了获得高度显著的结果，建议在更大的患者群体中进行前瞻性研究。关键词:儿童，味觉障碍，恶性肿瘤，造血，营养状况，中毒性神经病，牙齿状况

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Voprosy Detskoi Dietologii Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： The scientific journal Voprosy Detskoi Dietologii is included in the Scopus database. Publisher country is RU. The main subject areas of published articles are Food Science, Pediatrics, Perinatology, and Child Health, Nutrition and Dietetics, Клиническая медицина.