Rebamipide and proton pump inhibitors: benefits of combined use

Abstract

The article describes the benefits of rebamipide and proton pump inhibitors combination therapy for acid-related diseases. It was shown that rebamipide have a positive effect on various parts of the protective barrier of the epithelium in gastroesophageal reflux disease, chronic gastritis, peptic ulcer disease, functional dyspepsia, NSAID-induced gastrointestinal erosive and ulcerative lesions, and in the treatment of Helicobacter pylori infection. Key words: gastroesophageal reflux disease, proton pump inhibitors, NSAID gastropathy, rebamipide, functional dyspepsia, peptic ulcer disease, Helicobacter pylori