Нарушение водно-электролитного обмена у пациентов с камнями мочеточников после контактной литотрипсии

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL

Byulleten Sibirskoy Meditsiny Pub Date : 2016-03-16 DOI:10.20538/1682-0363-2012-2-40-43

Валентин Николаевич Павлов, А. М. Пушкарев, Алексеев Александр Владимирович, И. Г. Ракипов, Д. Р. Мусин, Адель Альбертович Измайлов

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Abstract

Urolithiasis is one of the most common urologic diseases, and 50% of patients with urolithiasis have ureteral stones. As with ureterolitiaze and in contact lithotripsy has been established development of glomerular and tubular dysfunction, which causes up to 9% of complications. Investigation of the parameters water-electrolyte metabolism carried out 52 patients with urolithiasis before and after contact ureterolitotripsi. Once installed KLT increase in glomerular filtration rate by 61% of the daily creatinine excretion a 43% urea 21%, sodium 28%, chlorides 55%, the concentration of ACTH 53% of cortisol 11%. In the urine increases the concentration of indicators of the glomerular and tubular dysfunction mikroalbumina 3 times, β2-microglobulin was 4,5 times, Ngala was 58%. The identified changes areapparently caused by intrarenal mechanisms only, because the major hormonal systems that regulate water and electrolyte metabolism, did not significantly change the parameters of its operation.

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接触石化病后输尿管结石患者缺水电解质紊乱

尿石症是最常见的泌尿系统疾病之一，50%的尿石症患者有输尿管结石。与输尿管结石术和接触式碎石术一样，已经确定肾小球和小管功能障碍的发展，这导致高达9%的并发症。对52例尿石症患者接触输尿管取石前后的水电解质代谢参数进行了调查。一旦安装KLT肾小球滤过率增加61%，每日肌酐排泄量增加43%，尿素21%，钠28%，氯化物55%，ACTH浓度增加53%，皮质醇增加11%。尿中肾小球和小管功能障碍指标微白蛋白浓度升高3倍，β2-微球蛋白升高4倍，β2-微球蛋白升高5倍，Ngala升高58%。已确定的变化显然仅由肾内机制引起，因为调节水和电解质代谢的主要激素系统并没有显着改变其运行参数。

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