From liver fat to full-blown metabolic disorder: the kidney as target organ

Abstract

study of subjects classified as advanced fibrosis by biomarker [high nonalcoholic fibrosis score (NFD) vs. low NFD; HR, 1.59], as well as in two studies where liver biopsy was available (fibrosis ≥ F3 vs. fibrosis < F3; HR, 2.75 and 3.25, respectively). The authors concluded that an effect of disease severity is very likely, but data are needed to support this evidence.