Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease

IF 0.6 4区医学 Q4 NUTRITION & DIETETICS

Revista De Nutricao-brazilian Journal of Nutrition Pub Date : 2022-01-01 DOI:10.1590/1678-9865202235e210219

Letícya Thaís Mendes Viana, B. E. S. D. A. Freitas

{"title":"Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease","authors":"Letícya Thaís Mendes Viana, B. E. S. D. A. Freitas","doi":"10.1590/1678-9865202235e210219","DOIUrl":null,"url":null,"abstract":"ABSTRACT Objective To investigate the relationship between calcidiol (25(OH)D3) concentrations and iron parameters in patients with chronic kidney disease. Methods This is a cross-sectional, descriptive, and quantitative study. The sample consisted of 86 adult patients of both sexes undergoing dialysis. 25(OH)D3 concentrations were determined by chemiluminescence; food consumption was assessed using 24-hour recalls, and the serum levels of hemoglobin, iron, ferritin, and transferrin saturation were assessed. Data analysis was performed using the program Stata, with a significance level of p<0.05. Results The results pointed to 25(OH)D3 concentrations compatible with sufficiency, iron levels consistent with normality, and ferritin and transferrin saturation above the reference values. The consumption of carbohydrates and lipids was higher in females. There was no relationship between the adequacy of 25(OH)D3 and the presence of anemia and iron parameters. Conclusion Considering that the mean serum levels of iron and 25(OH)D3 were adequate, it is suggested that resistance to erythropoietin and the inflammatory process may have contributed to the percentage of anemic individuals found in the study.","PeriodicalId":21305,"journal":{"name":"Revista De Nutricao-brazilian Journal of Nutrition","volume":"1 1","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista De Nutricao-brazilian Journal of Nutrition","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1590/1678-9865202235e210219","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}

引用次数: 0

Abstract

ABSTRACT Objective To investigate the relationship between calcidiol (25(OH)D3) concentrations and iron parameters in patients with chronic kidney disease. Methods This is a cross-sectional, descriptive, and quantitative study. The sample consisted of 86 adult patients of both sexes undergoing dialysis. 25(OH)D3 concentrations were determined by chemiluminescence; food consumption was assessed using 24-hour recalls, and the serum levels of hemoglobin, iron, ferritin, and transferrin saturation were assessed. Data analysis was performed using the program Stata, with a significance level of p<0.05. Results The results pointed to 25(OH)D3 concentrations compatible with sufficiency, iron levels consistent with normality, and ferritin and transferrin saturation above the reference values. The consumption of carbohydrates and lipids was higher in females. There was no relationship between the adequacy of 25(OH)D3 and the presence of anemia and iron parameters. Conclusion Considering that the mean serum levels of iron and 25(OH)D3 were adequate, it is suggested that resistance to erythropoietin and the inflammatory process may have contributed to the percentage of anemic individuals found in the study.

查看原文本刊更多论文

慢性肾病患者维生素D浓度及其与铁参数的关系

【摘要】目的探讨慢性肾病患者钙二醇(25(OH)D3)浓度与铁参数的关系。方法采用横断面、描述性和定量研究。样本包括86名接受透析的男女成年患者。化学发光法测定25(OH)D3浓度;采用24小时召回法评估食物消耗，并评估血清血红蛋白、铁、铁蛋白和转铁蛋白饱和度。数据分析采用Stata程序，差异有统计学意义，p<0.05。结果25(OH)D3浓度符合充分性，铁水平符合正常值，铁蛋白和转铁蛋白饱和度高于参考值。碳水化合物和脂类的摄入量在女性中更高。25(OH)D3的充足性与贫血和铁参数之间没有关系。结论考虑到铁和25(OH)D3的平均血清水平是足够的，提示对促红细胞生成素的抵抗和炎症过程可能是研究中发现的贫血个体百分比的原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista De Nutricao-brazilian Journal of Nutrition 医学-营养学

CiteScore

1.20

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Revista de Nutrição is former Revista de Nutrição da Puccamp, founded in 1988. It is a bimonthly publication every four months and it is of responsibility of the Centro de Ciências da Vida, da Pontifícia Universidade Católica de Campinas . It publishes articles that contribute to the study of Nutrition in its many sub-areas and interfaces; and is open to contributions of the national and international scientific communities.