Retrospective evaluation of canine anal sac carcinoma (260 cases) in Brazil: late detection and failures in lymph node evaluation

IF 0.8 4区 农林科学 Q3 VETERINARY SCIENCES
F. N. Paiva, S. Moreira, Laís Calazans Menescal Linhares, F. Sueiro, A. B. Nardi, P. Jark
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Abstract

ABSTRACT: Anal sac neoplasms are common in companion animals, and the epidemiological profile has been extensively described in international studies; however, national data are still lacking. Data on the Brazilian reality of anal sac carcinoma cases’ diagnosis and treatment are also scarce. The purpose of this study was to retrospectively evaluate cases of canine anal sac carcinoma and assess the profile of involvement, tumor size, and lymphatic invasion at the time of diagnosis. Information was obtained from Vetpat laboratory database, from 260 cases spanning a 12-year period (2010-2021). In histopathological evaluation at the time of diagnosis, data on sex, age, and race were described, as well as tumor size and lymphatic invasion. The presence of metastasis was also assessed in cases where lymph nodes were sampled. Simple descriptive statistical analysis was used to evaluate the data. Adult and elderly, female, and mixed-breed animals were more involved, indicating differences from international studies that can be attributed to sociocultural factors. In terms of tumor size, it was observed that 93% of the cases had the largest diameter above 2.5cm. Only 7% of the cases had the largest diameter below 2.5cm, demonstrating the often late diagnosis and the importance of rectal palpation examination during the general physical assessment of canine patients, particularly at an advanced age. Regarding lymphatic invasion and affected lymph nodes, 50% of the cases had lymphatic invasion described in the histopathological examination. However, only 5% of the lymph nodes were sent along with the primary tumor, indicating the disease’s aggressive behavior but with possible metastases underdiagnosed.
巴西犬肛囊癌(260例)的回顾性分析:淋巴结评估的晚期发现和失败
摘要:肛囊肿瘤在伴侣动物中很常见,其流行病学概况在国际研究中得到了广泛的描述;然而,国家数据仍然缺乏。关于巴西肛管癌病例的诊断和治疗的数据也很少。本研究的目的是回顾性评估犬肛囊癌病例,并评估其在诊断时的受累情况、肿瘤大小和淋巴浸润情况。从Vetpat实验室数据库获得的信息来自12年期间(2010-2021年)的260例病例。在诊断时的组织病理学评估中,描述了性别,年龄和种族的数据,以及肿瘤大小和淋巴浸润。在淋巴结取样的情况下也评估了转移的存在。采用简单描述性统计分析对资料进行评价。成年动物、老年动物、雌性动物和杂交动物的参与程度更高,这表明与国际研究的差异可归因于社会文化因素。在肿瘤大小方面,93%的病例最大直径大于2.5cm。只有7%的病例最大直径小于2.5cm,这表明直肠触诊检查在犬患者的一般体格评估中往往较晚诊断和重要性,特别是在老年犬患者中。在淋巴浸润及受累淋巴结方面,50%的病例在组织病理学检查中描述有淋巴浸润。然而,只有5%的淋巴结随原发肿瘤一起转移,这表明该疾病具有侵袭性,但可能存在未确诊的转移。
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来源期刊
Pesquisa Veterinaria Brasileira
Pesquisa Veterinaria Brasileira 农林科学-兽医学
CiteScore
1.30
自引率
16.70%
发文量
41
审稿时长
9-18 weeks
期刊介绍: Pesquisa Veterinária Brasileira - Brazilian Journal of Veterinary Research (http://www.pvb.com.br), edited by the Brazilian College of Animal Pathology in partnership with the Brazilian Agricultural Research Organization (Embrapa) and in collaboration with other veterinary scientific associations, publishes original papers on animal diseases and related subjects. Critical review articles should be written in support of original investigation. The editors assume that papers submitted are not being considered for publication in other journals and do not contain material which has already been published. Submitted papers are peer reviewed. The abbreviated title of Pesquisa Veterinária Brasileira is Pesqui. Vet. Bras.
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