Brain mapping optimization: DES characterization towards improved sensitivityA. Bouadel

Abstract

Improving the functional mapping quality means overcoming the effect of boundary conditions affecting its sensitivity under the false negative impact without forgetting the manageable impact of false positives on its specificity. This is a simulation study of the functional brain mapping has been done by neuronal computational modeling in correlation with a comparative retrospective analysis. However, the results show the optimization of the parameters threshold in DES, as intensity threshold, its increase by the CSF resistivity and the extremum duration of the electrical signal in direct application. Therefore, the awake surgery becomes not only a revolutionary technique; because of the extent of the resection, which is currently done according to functional imperative, unlike the onco-anatomical limits during the classical paradigm; but to free up new therapeutic perspective towards a functional, personalized and maximalist surgical neuro-oncology without malignant transformation.